fac-[Re(CO)3(L3)(H2O)][NO3]
fac-[Re(CO)3(L3)(H2O)][NO3] (compound 3), the rhenium(I) tricarbonyl aqua complex, is an anticancer agent associated with mitochondrial dysfunction. fac-[Re(CO)3(L3)(H2O)][NO3] is cytotoxic to prostate cancer cells with IC50=0.32 μM (PC-3 cells). fac-[Re(CO)3(L3)(H2O)][NO3] mainly accumulates in mitochondria, down-regulates ATP production in PC3 cells, and promotes paraptosis. However, fac-[Re(CO)3(L3)(H2O)][NO3] did not induce necrosis, apoptosis and autophagy.
For research use only. We do not sell to patients.
- Formula: C25H17N6O8Re
- Molecular Weight:715.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
![fac-[Re(CO)3(L3)(H2O)][NO3] Chemical Structure](https://file.medchemexpress.com/product_pic/hy-155719.gif "Click to View fac-[Re(CO)3(L3)(H2O)][NO3] Chemical Structure")
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 715.64
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Formula C25H17N6O8Re
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SMILES
[OH2][Re+]1([N]2=CC=CC3=C2C4=C(C5=C3N=C(C6=CNC7=C6C=C(OC)C=C7)N5)C=CC=[N]41)([C]=O)([C]=O)[C]=O.[O-][N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
fac-[Re(CO)3(L3)(H2O)][NO3] Related Classifications
HY-155719 Related Classifications
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