PBE-AMF
PBE-AMF is a prodrug that activates H2O2 with anticancer activity. PBE-AMF impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBE-AMF potently and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.
For research use only. We do not sell to patients.
- Formula: C30H34BN3O6
- Molecular Weight:543.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 543.42
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Formula C30H34BN3O6
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SMILES
O=C(C1=CC(NC(OCC2=CC=C(B3OC(C)(C)C(C)(C)O3)C=C2)=O)=CC4=C1C5=CC=C4)N(CCN(C)C)C5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)