3-O-(2'E,4'E-Decadienoyl)-ingenol
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 466663-11-6
- Formula: C30H42O6
- Molecular Weight:498.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
3-O-(2'E,4'E-Decadienoyl)-ingenol (5-30 μg/mL; 24 hours) shows cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L-O2 and GES-1 cells
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Concentration:5 μg/mL, 10 μg/mL,15 μg/mL, 20 μg/mL, 25 μg/mL, 30 μg/mL
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Incubation Time:24 hours
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Result:Showed cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships.
Chemical Information
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CAS No. 466663-11-6
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Molecular Weight 498.65
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Formula C30H42O6
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SMILES
CC1=C[C@]23[C@](O)([C@@H](C(CO)=C[C@H](C3=O)[C@H]4[C@@H](C[C@H]2C)C4(C)C)O)[C@H]1OC(/C=C/C=C/CCCCC)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)