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Cat. No.: HY-155665

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Gly-amide-OMe-Cbz

NH2-CH-CONH-CH2-O-CH2-Cbz (Page 3, Compound E) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC).

For research use only. We do not sell to patients.

CAS No.: 2264011-95-0
Formula: C₁₂H₁₆N₂O₄
Molecular Weight:252.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

Gly-amide-OMe-Cbz Chemical Structure

CAS No.: 2264011-95-0

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Use of MCE Products

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Biological Activity

Description

NH2-CH-CONH-CH2-O-CH2-Cbz (Page 3, Compound E) is an ADC linker that can be used for the synthesis of antibody-conjugated active molecules (ADC)^[1].

All ADC Linkers Isoforms :

Chemical Information

CAS No. 2264011-95-0
Molecular Weight 252.27
Formula C₁₂H₁₆N₂O₄
SMILES

O=C(OCC1=CC=CC=C1)COCNC(CN)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Molecular Biology

Polyacrylamide gel electrophoresis (PAGE) (<1 kb)
Gel electrophoresis is a method for separating biological macromolecules (such as nucleic acids or proteins) by forcing them through a gel matrix under an electric field.
Protocol for Protein Electrophoresis
Protein electrophoresis separates proteins in a polyacrylamide gel under an electric field; in SDS-PAGE, sodium dodecyl sulfate denatures proteins and gives them a broadly similar negative charge-to-mass ratio, so migration mainly reflects apparent molecular mass through the gel matrix. The readout is a stained protein band pattern: band position estimates apparent molecular mass using protein standards, band intensity reflects relative protein abundance within the linear range of staining/detection, and changes in band pattern can reflect protein expression, degradation, purification, or sample composition.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Luo QD, et al. Preparation method of ADC linker. CN113527418A.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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