1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. KCa2 channel modulator 1

KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype.

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KCa2 channel modulator 1 Chemical Structure

KCa2 channel modulator 1 Chemical Structure

CAS No. : 1019106-73-0

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Description

KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype[1].

Molecular Weight

331.78

Formula

C16H15ClFN5

CAS No.
SMILES

CC1=CC(NC2=CC=C(F)C(Cl)=C2)=NC(N3N=C(C)C=C3C)=N1

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KCa2 channel modulator 1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KCa2 channel modulator 1
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HY-142723
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