Palmitoyl tetrapeptide-20
Based on 1 Customer Validation
Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 can be used in research on preventing hair loss and improving hair graying.
For research use only. We do not sell to patients.
- Purity: 99.21%
- Formula: C38H70N6O8
- Molecular Weight:739.00
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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MC1R |
SIRT1 |
Palmitoyl tetrapeptide-20 (0.1-1 μM; 72 h) promotes melanin production in human melanocytes[1].
Palmitoyl tetrapeptide-20 (18 h) reduces intracellular H2O2 levels in human follicle dermal papilla cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 739.00
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Formula C38H70N6O8
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Color White to off-white
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Synonyms
PTP20
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Sequence
{Pal}-Pro-Glu-Lys-Lys
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Sequence Shortening
{Pal}-PEKK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 28.57 mg/mL (38.66 mM; adjust pH to 4 with 1 M HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
0.1 M HCl : 5 mg/mL (6.77 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| 0.1 M HCl / DMSO | 1 mM | 1.3532 mL | 6.7659 mL | 13.5318 mL | 33.8295 mL |
| 5 mM | 0.2706 mL | 1.3532 mL | 2.7064 mL | 6.7659 mL | |
| DMSO | 10 mM | 0.1353 mL | 0.6766 mL | 1.3532 mL | 3.3829 mL |
| 15 mM | 0.0902 mL | 0.4511 mL | 0.9021 mL | 2.2553 mL | |
| 20 mM | 0.0677 mL | 0.3383 mL | 0.6766 mL | 1.6915 mL | |
| 25 mM | 0.0541 mL | 0.2706 mL | 0.5413 mL | 1.3532 mL | |
| 30 mM | 0.0451 mL | 0.2255 mL | 0.4511 mL | 1.1276 mL |
Palmitoyl tetrapeptide-20 Related Classifications
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