Nrf2 activator-10
Based on 1 Customer Validation
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
For research use only. We do not sell to patients.
- Purity: 98.65%
- CAS No.: 75483-04-4
- Formula: C13H12ClNO3
- Molecular Weight:265.69
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Apoptosis Compound Library
HY-L003
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Immunology/Inflammation Compound Library
HY-L007
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NF-κB Signaling Compound Library
HY-L014
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Stem Cell Signaling Compound Library
HY-L017
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Antioxidant Compound Library
HY-L037
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Oxygen Sensing Compound Library
HY-L045
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Ferroptosis Compound Library
HY-L051
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Anti-Cancer Metabolism Compound Library
HY-L083
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Anti-Obesity Compound Library
HY-L087
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Transcription Factor-Targeted Library
HY-L090
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Anti-Pulmonary Fibrosis Compound Library
HY-L125
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Cell Death Library
HY-L162
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Radioprotector Library
HY-L178
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Anti-Fibrosis Compound Library
HY-L185
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Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
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High-Throughput Bioactive Compound Library
HY-L205
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Lactylation Compound Library
HY-L249
Biological Activity
Chemical Information
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CAS No. 75483-04-4
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Appearance Solid
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Molecular Weight 265.69
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Formula C13H12ClNO3
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Color White to off-white
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SMILES
O=C(C1=C(Cl)C2=C(C=CC=C2)N(C)C1=O)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (188.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7638 mL | 18.8189 mL | 37.6378 mL | 94.0946 mL |
| 5 mM | 0.7528 mL | 3.7638 mL | 7.5276 mL | 18.8189 mL | |
| 10 mM | 0.3764 mL | 1.8819 mL | 3.7638 mL | 9.4095 mL | |
| 15 mM | 0.2509 mL | 1.2546 mL | 2.5092 mL | 6.2730 mL | |
| 20 mM | 0.1882 mL | 0.9409 mL | 1.8819 mL | 4.7047 mL | |
| 25 mM | 0.1506 mL | 0.7528 mL | 1.5055 mL | 3.7638 mL | |
| 30 mM | 0.1255 mL | 0.6273 mL | 1.2546 mL | 3.1365 mL | |
| 40 mM | 0.0941 mL | 0.4705 mL | 0.9409 mL | 2.3524 mL | |
| 50 mM | 0.0753 mL | 0.3764 mL | 0.7528 mL | 1.8819 mL | |
| 60 mM | 0.0627 mL | 0.3136 mL | 0.6273 mL | 1.5682 mL | |
| 80 mM | 0.0470 mL | 0.2352 mL | 0.4705 mL | 1.1762 mL | |
| 100 mM | 0.0376 mL | 0.1882 mL | 0.3764 mL | 0.9409 mL |
Nrf2 activator-10 Related Classifications
HY-124834 Related Classifications
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