1. Cell Cycle/DNA Damage
    Metabolic Enzyme/Protease
  2. DNA/RNA Synthesis
    Endogenous Metabolite
  3. 2-O-Methylcytosine

2-O-Methylcytosine 

Cat. No.: HY-69014 Purity: >97.0%
Handling Instructions

2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase.

For research use only. We do not sell to patients.

2-O-Methylcytosine Chemical Structure

2-O-Methylcytosine Chemical Structure

CAS No. : 3289-47-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
500 mg USD 120 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

The damaged nucleobases can cause DNA mutation, resulting in various diseases such as cancer[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

125.13

Formula

C₅H₇N₃O

CAS No.

3289-47-2

SMILES

NC1=NC(OC)=NC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 60 mg/mL (479.50 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.9917 mL 39.9584 mL 79.9169 mL
5 mM 1.5983 mL 7.9917 mL 15.9834 mL
10 mM 0.7992 mL 3.9958 mL 7.9917 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 3 mg/mL (23.98 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3 mg/mL (23.98 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 3 mg/mL (23.98 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

2-O-MethylcytosineDNA/RNA SynthesisEndogenous MetaboliteadductDNAO-alkylateddamagenucleobaseInhibitorinhibitorinhibit

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Product Name:
2-O-Methylcytosine
Cat. No.:
HY-69014
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