BChE/MAO-B-IN-1
BChE/MAO-B-IN-1 (compound 7) is a dual BChE/MAO-B inhibitor with IC50 values of 375 nM and 20 nM, respectively. BChE/MAO-B-IN-1 protects against oxidative damage induced by H2O2 and 6-OHDA in SH-SY5Y cells. BChE/MAO-B-IN-1 can penetrate the central nervous system in a cell model that mimics the blood-brain barrier. BChE/MAO-B-IN-1 can be used in the study of neurological diseases such as Alzheimer's disease (AD).
For research use only. We do not sell to patients.
- Formula: C25H25NO4S
- Molecular Weight:435.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
BChE 375 nM (IC50) |
MAO-B 20 nM (IC50) |
Chemical Information
-
Molecular Weight 435.54
-
Formula C25H25NO4S
-
SMILES
O=C1C=C(CO)C2=C(O1)C=C(OCC3=CC=C(CN(C)CCC4=CSC=C4)C=C3)C=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)