1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride 

Cat. No.: HY-112617B
Handling Instructions

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer.

For research use only. We do not sell to patients.

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride Chemical Structure

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride Chemical Structure

CAS No. : 2376990-30-4

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Description

Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride incorporates an E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer[1].

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

498.91

Formula

C21H27ClN4O8

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
Cat. No.:
HY-112617B
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