1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugates
  3. Pomalidomide-PEG6-NH2 hydrochloride

Pomalidomide-PEG6-NH2 hydrochloride 

Cat. No.: HY-136161
Handling Instructions

Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Pomalidomide-PEG6-NH2 hydrochloride Chemical Structure

Pomalidomide-PEG6-NH2 hydrochloride Chemical Structure

CAS No. : 2341841-01-6

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Description

Pomalidomide-PEG6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.

IC50 & Target[1]

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

574.02

Formula

C25H36ClN3O10

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Pomalidomide-PEG6-NH2 hydrochloride
Cat. No.:
HY-136161
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