2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan
Based on 1 Customer Validation
2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan (HY-13631). 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody.
For research use only. We do not sell to patients.
- Purity : 98.10%
- CAS No.: 2964536-59-0
- Formula: C53H55FN10O13S
- Molecular Weight:1091.13
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Camptothecins |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2964536-59-0
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Appearance Solid
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Molecular Weight 1091.13
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Formula C53H55FN10O13S
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Color Light yellow to yellow
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SMILES
CS(C1=NC=C(C=N1)C#CCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (91.65 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.9165 mL | 4.5824 mL | 9.1648 mL | 22.9120 mL |
| 5 mM | 0.1833 mL | 0.9165 mL | 1.8330 mL | 4.5824 mL | |
| 10 mM | 0.0916 mL | 0.4582 mL | 0.9165 mL | 2.2912 mL | |
| 15 mM | 0.0611 mL | 0.3055 mL | 0.6110 mL | 1.5275 mL | |
| 20 mM | 0.0458 mL | 0.2291 mL | 0.4582 mL | 1.1456 mL | |
| 25 mM | 0.0367 mL | 0.1833 mL | 0.3666 mL | 0.9165 mL | |
| 30 mM | 0.0305 mL | 0.1527 mL | 0.3055 mL | 0.7637 mL | |
| 40 mM | 0.0229 mL | 0.1146 mL | 0.2291 mL | 0.5728 mL | |
| 50 mM | 0.0183 mL | 0.0916 mL | 0.1833 mL | 0.4582 mL | |
| 60 mM | 0.0153 mL | 0.0764 mL | 0.1527 mL | 0.3819 mL | |
| 80 mM | 0.0115 mL | 0.0573 mL | 0.1146 mL | 0.2864 mL |
2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan Related Classifications
HY-157813 Related Classifications
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