1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 2'-O-TBDMS-rG(iBu)

2'-O-TBDMS-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.

For research use only. We do not sell to patients.

2'-O-TBDMS-rG(iBu)

2'-O-TBDMS-rG(iBu) Chemical Structure

CAS No. : 182007-86-9

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Description

2'-O-TBDMS-rG(iBu) is a monomeric raw material that can be used for nucleic acid synthesis.

Molecular Weight

467.59

Formula

C20H33N5O6Si

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N(C=N2)C3=C2C(N=C(NC(C(C)C)=O)N3)=O)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (213.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1386 mL 10.6931 mL 21.3863 mL
5 mM 0.4277 mL 2.1386 mL 4.2773 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1386 mL 10.6931 mL 21.3863 mL 53.4656 mL
5 mM 0.4277 mL 2.1386 mL 4.2773 mL 10.6931 mL
10 mM 0.2139 mL 1.0693 mL 2.1386 mL 5.3466 mL
15 mM 0.1426 mL 0.7129 mL 1.4258 mL 3.5644 mL
20 mM 0.1069 mL 0.5347 mL 1.0693 mL 2.6733 mL
25 mM 0.0855 mL 0.4277 mL 0.8555 mL 2.1386 mL
30 mM 0.0713 mL 0.3564 mL 0.7129 mL 1.7822 mL
40 mM 0.0535 mL 0.2673 mL 0.5347 mL 1.3366 mL
50 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0693 mL
60 mM 0.0356 mL 0.1782 mL 0.3564 mL 0.8911 mL
80 mM 0.0267 mL 0.1337 mL 0.2673 mL 0.6683 mL
100 mM 0.0214 mL 0.1069 mL 0.2139 mL 0.5347 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2'-O-TBDMS-rG(iBu)
Cat. No.:
HY-47393
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