Spongosine
Based on 1 Customer Validation
Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 95.43%
- CAS No.: 24723-77-1
- Formula: C11H15N5O5
- Molecular Weight:297.27
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 24723-77-1
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Appearance Solid
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Molecular Weight 297.27
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Formula C11H15N5O5
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Color White to off-white
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SMILES
NC1=NC(OC)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3
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Synonyms
2-Methoxyadenosine; 2-O-Methylisoguanosine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (840.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [Content Brief]
[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3639 mL | 16.8197 mL | 33.6395 mL | 84.0986 mL |
| 5 mM | 0.6728 mL | 3.3639 mL | 6.7279 mL | 16.8197 mL | |
| 10 mM | 0.3364 mL | 1.6820 mL | 3.3639 mL | 8.4099 mL | |
| 15 mM | 0.2243 mL | 1.1213 mL | 2.2426 mL | 5.6066 mL | |
| 20 mM | 0.1682 mL | 0.8410 mL | 1.6820 mL | 4.2049 mL | |
| 25 mM | 0.1346 mL | 0.6728 mL | 1.3456 mL | 3.3639 mL | |
| 30 mM | 0.1121 mL | 0.5607 mL | 1.1213 mL | 2.8033 mL | |
| 40 mM | 0.0841 mL | 0.4205 mL | 0.8410 mL | 2.1025 mL | |
| 50 mM | 0.0673 mL | 0.3364 mL | 0.6728 mL | 1.6820 mL | |
| 60 mM | 0.0561 mL | 0.2803 mL | 0.5607 mL | 1.4016 mL | |
| 80 mM | 0.0420 mL | 0.2102 mL | 0.4205 mL | 1.0512 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3364 mL | 0.8410 mL |
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