DMTr-2'-O-C22-rU-3'-CE-phosphoramidite
Based on 1 Customer Validation
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rU-3'-CE-phosphoramidite can be used for the construction and mechanistic studies of nucleic acid molecules.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2923115-86-8
- 分子式: C61H91N4O9P
- 分子量:1055.37
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
DMTr‑2'-O‑C22‑rU‑3'-CE‑phosphoramidite (compound 111) can be used to site-specifically introduce a lipophilic 2'-O-C22 modification at the uridine site in oligonucleotide synthesis, enabling the construction of double-stranded RNA (dsRNA) molecules capable of extrahepatic delivery[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2923115-86-8
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性状 Solid
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分子量 1055.37
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分子式 C61H91N4O9P
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SMILES
COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](OCCCCCCCCCCCCCCCCCCCCCC)[C@H](N5C(NC(C=C5)=O)=O)O4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 20 mg/mL (18.95 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9475 mL | 4.7377 mL | 9.4753 mL | 23.6884 mL |
| 5 mM | 0.1895 mL | 0.9475 mL | 1.8951 mL | 4.7377 mL | |
| 10 mM | 0.0948 mL | 0.4738 mL | 0.9475 mL | 2.3688 mL | |
| 15 mM | 0.0632 mL | 0.3158 mL | 0.6317 mL | 1.5792 mL |