DMTr-2'-O-C22-rU-3'-CE-phosphoramidite
Based on 1 Customer Validation
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rU-3'-CE-phosphoramidite can be used for the construction and mechanistic studies of nucleic acid molecules.
For research use only. We do not sell to patients.
- CAS No.: 2923115-86-8
- Formula: C61H91N4O9P
- Molecular Weight:1055.37
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
DMTr‑2'-O‑C22‑rU‑3'-CE‑phosphoramidite (compound 111) can be used to site-specifically introduce a lipophilic 2'-O-C22 modification at the uridine site in oligonucleotide synthesis, enabling the construction of double-stranded RNA (dsRNA) molecules capable of extrahepatic delivery[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2923115-86-8
-
Appearance Solid
-
Molecular Weight 1055.37
-
Formula C61H91N4O9P
-
SMILES
COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](OCCCCCCCCCCCCCCCCCCCCCC)[C@H](N5C(NC(C=C5)=O)=O)O4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 20 mg/mL (18.95 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (278 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9475 mL | 4.7377 mL | 9.4753 mL | 23.6884 mL |
| 5 mM | 0.1895 mL | 0.9475 mL | 1.8951 mL | 4.7377 mL | |
| 10 mM | 0.0948 mL | 0.4738 mL | 0.9475 mL | 2.3688 mL | |
| 15 mM | 0.0632 mL | 0.3158 mL | 0.6317 mL | 1.5792 mL |
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite Related Classifications
HY-200314 Related Classifications
Powered by Bioz