1. Protein Tyrosine Kinase/RTK
    Anti-infection
  2. FGFR
    HSV
    VEGFR
  3. Surfen dihydrochloride

Surfen dihydrochloride (Synonyms: Aminoquincarbamide dihydrochloride)

Cat. No.: HY-122704A
Handling Instructions

Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection.

For research use only. We do not sell to patients.

Surfen dihydrochloride Chemical Structure

Surfen dihydrochloride Chemical Structure

CAS No. : 5424-37-3

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Description

Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection[1].

IC50 & Target

FGFR2

5 μM (IC50)

HSV-1

 

Molecular Weight

445.34

Formula

C21H22Cl2N6O

CAS No.
SMILES

O=C(NC1=CC=C2N=C(C)C=C(N)C2=C1)NC3=CC=C4N=C(C)C=C(N)C4=C3.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Surfen dihydrochloride
Cat. No.:
HY-122704A
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