1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 1,2'-O-Dimethylguanosine

1,2'-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7).

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1,2'-O-Dimethylguanosine Chemical Structure

1,2'-O-Dimethylguanosine Chemical Structure

CAS No. : 73667-71-7

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Description

1,2'-O-Dimethylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Molecular Weight

311.29

Formula

C12H17N5O5

CAS No.
SMILES

OC[C@@H]1[C@@H](O)[C@@H](OC)[C@H](N(C=N2)C3=C2C(N(C)C(N)=N3)=O)O1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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1,2'-O-Dimethylguanosine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1,2'-O-Dimethylguanosine
Cat. No.:
HY-137406
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