1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2 (Synonyms: Cereblon Ligand-Linker Conjugates 12 TFA; E3 Ligase Ligand-Linker Conjugates 23 TFA)

Cat. No.: HY-112600A Purity: 96.77%
Handling Instructions

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2 Chemical Structure

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2 Chemical Structure

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Description

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

IC50 & Target

Cereblon

 

Molecular Weight

648.58

Formula

C₂₇H₃₅F₃N₄O₁₁

SMILES

OC(C(F)(F)F)=O.O=C(NCCOCCCOCCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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Keywords:

Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2Cereblon Ligand-Linker Conjugates 12E3 Ligase Ligand-Linker Conjugates 23E3 Ligase Ligand-Linker ConjugateInhibitorinhibitorinhibit

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Product name:
Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2
Cat. No.:
HY-112600A
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