2435572-49-7
Chemical Structure
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA
Synonym(s): Cereblon Ligand-Linker Conjugates 12 TFA; E3 Ligase Ligand-Linker Conjugates 23 TFA
- CAS No.: 2435572-49-7
- Formula:C27H35F3N4O11
- Molecular Weight:648.58
IUPAC Name: N-(2-(3-(3-(2-aminoethoxy)propoxy)propoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide 2,2,2-trifluoroacetate
InChIKey: XLQMWZARPGGRIS-UHFFFAOYSA-N
SMILES: OC(C(F)(F)F)=O.O=C(NCCOCCCOCCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
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Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA | 99.28% | Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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