1. PROTAC
  2. PROTAC Linker
  3. Tos-PEG2-O-Propargyl

Tos-PEG2-O-Propargyl 

Cat. No.: HY-130162 Purity: 98.47%
Handling Instructions

Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458).

For research use only. We do not sell to patients.

Tos-PEG2-O-Propargyl Chemical Structure

Tos-PEG2-O-Propargyl Chemical Structure

CAS No. : 1119249-30-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 80 In-stock
Estimated Time of Arrival: December 31
10 mg USD 130 In-stock
Estimated Time of Arrival: December 31
50 mg USD 350 In-stock
Estimated Time of Arrival: December 31
100 mg USD 500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458)[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight

298.35

Formula

C₁₄H₁₈O₅S

CAS No.

1119249-30-7

SMILES

C#CCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

Tos-PEG2-O-PropargylPROTAC LinkerInhibitorinhibitorinhibit

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Tos-PEG2-O-Propargyl
Cat. No.:
HY-130162
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