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Candida albicans NCIM 3471

" in MedChemExpress (MCE) Product Catalog:

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0101

Fluconazole Maximum Cited Publications 21 Publications Verification UK-49858	Environmental Pollutants Antibiotic Fungal Bacterial	Infection Cancer
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-Y1422D

*Lipase,Candida* antarctica (Immobilized)**	Environmental Pollutants Lipase	Others
Lipase,Candida antarctica (Immobilized) is an immobilized lipase isolated from Candida antarctica fraction B. Lipase,Candida antarctica (Immobilized) features high stability and selectivity. Lipase,Candida antarctica (Immobilized) is widely used in fields such as chemical synthesis, food oil modification, and biodiesel production .

HY-W016288

Naphthalene-2,3-dicarboxaldehyde 1 Publications Verification 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde	Fungal	Infection
Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a K_i value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .

HY-E70313

*Lipase,Candida* antarctica (Immobilized on hydrophilic carrier)** Candida antarctica lipase B	Biochemical Assay Reagents	Others
Lipase,Candida antarctica (Immobilized on hydrophilic carrier) (Candida antarctica lipase B) is a lipase derived from Candida antarctica and immobilized on a hydrophilic carrier. Lipase,Candida antarctica (Immobilized on hydrophilic carrier) is a green catalyst that can be used to catalyze polymer synthesis .

HY-P10304

Cyclo(Arg-Pro) Cyclo(Pro-Arg)	Fungal	Others
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .

HY-Y1422H

*Lipase,Candida* cylindracea (Immobilized)**	Environmental Pollutants Biochemical Assay Reagents Lipase	Others
Lipase, Candida cylindracea (Immobilized) is an immobilized hydrolase and biocatalyst with relaxed positional and substrate specificity. Lipase, Candida cylindracea (Immobilized) can target primary and secondary ester bonds to completely hydrolyze triglycerides into fatty acids and glycerol, producing only trace amounts of monoglycerides. Lipase, Candida cylindracea (Immobilized) exhibits chain specificity, with a relatively fast hydrolysis rate for oleic acid and lauric acid chains, and the slowest hydrolysis rate for stearic acid chains. Lipase, Candida cylindracea (Immobilized) shows high catalytic activity toward long-chain triglycerides under the conditions of pH 8.0 and 37°C .

HY-P2124

Cyclo(L-Trp-L-Trp)	Antibiotic Bacterial	Infection
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research .

HY-N3307

(+)-Medioresinol 1 Publications Verification	Bacterial Fungal Reactive Oxygen Species (ROS) Apoptosis MMP Interleukin Related PI3K Akt mTOR PPAR PGC-1α Pyroptosis	Infection Neurological Disease Inflammation/Immunology
(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke .

HY-B1237

Suloctidil	Calcium Channel Fungal	Cardiovascular Disease Infection
Suloctidil is an orally active calcium channel blocker and antifungal agent. Suloctidil antagonizes vasoconstriction induced by norepinephrine, angiotensin and serotonin. Suloctidil inhibits platelet function and exhibits neuroprotective effects. Suloctidil exerts inhibitory effects on Candida albicans biofilm and virulence. Suloctidil can be used in research on vasospasm relief, antithrombosis and superficial candidiasis .

HY-B2153

Tetraethylenepentamine pentahydrochloride	Cuproptosis Bacterial	Infection
Tetraethylenepentamine pentahydrochloride is an orally active copper chelator and copper mobilizer. Tetraethylenepentamine pentahydrochloride exhibits growth inhibitory and hypolipidemic properties. Tetraethylenepentamine pentahydrochloride significantly increases urinary copper excretion and reduces renal copper accumulation in copper overload models, but does not significantly alter hepatic copper levels. Tetraethylenepentamine pentahydrochloride exerts growth inhibitory effects on Candida albicans and Fluconazole (HY-B0101)-resistant strains, and can be widely used in studies related to Wilson's disease and Candida infections .

HY-N7626

Eleutherol	Fungal Glycosidase	Infection
Eleutherol is a naphthalene isolated from E. americana with antifungal activities . Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL . Eleutherol inhibits α-glucosidase function with an IC₅₀>1.00 mM .

HY-P2921D

*Uricase, candida* utilis** Uox, Candida utilis	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uricase, candida utilis (Uox, candida utilis) is a uricase (urate oxidase) derived from Candida utilis. Uricase, candida utilis converts uric acid into allantoin. The absence of Uricase in mammals causes kidney diseases resulting from uric acid accumulation. Uricase, candida utilis can be used for research on chronic refractory gout and hyperuricemia .

HY-B0101R

Fluconazole (Standard) UK-49858 (Standard)	Reference Standards Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-B1316

Trimetozine	Fungal	Infection Neurological Disease
Trimetozine is an Antifungal agent and sedative. Trimetozine exhibits antibacterial activity against Candida albicans, Candida glabrata, and Miconazole (HY-B0454)-resistant Candida glabrata cultures. Trimetozine exerts a sedative effect. Trimetozine can be used in research related to candidiasis and anxiety disorders .

HY-W012126

2,6-Dichlorodiphenylamine 2,6-Dichloro-N-phenylaniline	Bacterial	Infection Cancer
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.

HY-P10304A

Cyclo(Arg-Pro) TFA Cyclo(Pro-Arg) TFA	Fungal	Infection
Cyclo (Arg-Pro) TFA is a chitinase inhibitor. Cyclo (Arg-Pro) TFA disrupts cell separation and morphological transition of yeast by inhibiting chitinase activity. Cyclo (Arg-Pro) TFA prevents cell separation of Saccharomyces cerevisiae, leading to the formation of grape-like cell clusters, without inhibiting cell growth. Cyclo (Arg-Pro) TFA blocks the morphological transition of Candida albicans from yeast form to hyphal form, without inhibiting cell growth .

HY-W014665

N-Phthaloylglycine Phthaloyl glycine	Bacterial Fungal	Infection
N-Phthaloylglycine (Phthaloyl glycine) is a Type II fragmentary hapten (FX-type) with antimicrobial activity. N-Phthaloylglycine acts against Candida albicans, Escherichia coli, and Staphylococcus epidermidis. N-Phthaloylglycine can be used for the research of fungal and bacterial infection .

HY-163540

NP-BTA	Aminoacyl-tRNA Synthetase Fungal	Infection
NP-BTA is an allosteric inhibitor for glutaminyl-tRNA synthetase (GlnRS). NP-BTA exhibits antifungal efficacy against Candida albicans, with MIC₅₀ of 6.25 μM .

HY-W1127089

Antifungal agent 136	Fungal Cytochrome P450 Interleukin Related	Infection Inflammation/Immunology
Antifungal agent 136 is a CYP51 inhibitor and antifungal agent. Antifungal agent 136 downregulates the expression of interleukin-6 to alleviate inflammatory responses. Antifungal agent 136 exhibits activity against both drug-sensitive and drug-resistant Candida albicans strains. Antifungal agent 136 can be used in the research of fungal infections and inflammatory diseases .

HY-W587956

α-Guaiene	Fungal	Infection
α-Guaiene is a natural sesquiterpene and fungicidal agent found in Pogostemon cablin (patchouli) essential oil. α-Guaiene suppresses the growth of Aspergillus niger, Candida albicans, Microsporum gypseum, and Trichophyton mentagrophytes. α-Guaiene can be used for the study of fungal infection .

HY-P11170

D-Cateslytin	Fungal	Infection
D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis .

HY-E70888

*Lipase, Candida* antarctica, expressed in Aspergillus niger**	Lipase	Others
Lipase, Candida antarctica, expressed in Aspergillus niger, is a serine hydrolase, which belongs to the α/β hydrolase fold family .

HY-P2979A

*Invertase, candida* sp.** β-D-Fructofuranosidase, Candida sp.	Biochemical Assay Reagents	Others
Invertase from Candida sp. is responsible for catalyzing the hydrolysis of sucrose into glucose and fructose and is widely used in the field of carbohydrate processing. Invertase from Candida sp. can be used for enzymatic determination of sucrose concentration as well as for structural analysis of carbohydrates containing β-D-fructofuranosyl residues .

HY-143335

Antifungal agent 52	Fungal	Infection
Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization .

HY-P10603

SP1	Antibiotic Bacterial	Infection
SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection .

HY-180521

Piroctone	Fungal	Infection Cancer
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including *Candida* species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research .

HY-150584

Chitin synthase inhibitor 3	Fungal	Infection
Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC₅₀ value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity .

HY-129260

Kanosamine 3-Amino-3-deoxyglucose	Fungal	Infection
Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic against Saccharomyces cerevisiae and human pathogenic fungi Candida albicans. Kanosamine exhibits antifungal activity through inhibition of cell wall synthesis and inhibition of GlcN-6-P synthase with phosphorylated kanosamine-6-phosphate in cytoplasma .

HY-135445

Prolylrapamycin 21-Norrapamycin	Fungal	Infection
Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin (HY-10219). Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL .

HY-N2105

(-)-Dicentrine L-Dicentrine	Fungal Bacterial	Infection
(-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans .

HY-N15640

Filiformin (-)-Filiformin	Bacterial	Infection Inflammation/Immunology Cancer
Filiformin ((-)-Filiformin) is a sesquiterpene compound that can be isolated from Laurencia filiformis forma heteroclada. Filiformin exhibits certain cytotoxicity against P388 and BSC-1 cells. Filiformin has antimicrobial activity against Bacillus subtilis, Trichophyton mentagrophytes and Candida albicans. In addition, Filiformin can inhibit oxygen uptake in isolated rat liver mitochondria at a concentration of 150 μM .

HY-N11772

Mutanocyclin	Fungal	Infection
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

HY-156090

PK-10	Mitochondrial Metabolism Fungal	Infection
PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction .

HY-P11191

AR-23	Bacterial	Infection
AR-23 is a melittin-related antimicrobial peptide that can be isolated from Rana tagoi. AR-23 exhibits broad-spectrum growth inhibitory activity against aerobic bacteria, the opportunistic yeast pathogen Candida albicans and clinical isolates of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). AR-23 can be used for antimicrobial research .

HY-143405

Antifungal agent 24	Fungal	Infection
Antifungal agent 24 (Compound 6) is an antifungal agent against **Candida albicans** with a MIC value of 0.03 μg/mL .

HY-N16444

Sporminarin B	Fungal Bacterial	Infection
Sporminarin B is an antibacterial and antifungal agent. Sporminarin B exhibits inhibitory activity against microorganisms such as Candida albicans and Staphylococcus aureus .

HY-146116

Antifungal agent 32	Fungal	Infection
Antifungal agent 32 (compound 1a) is a potent antifungal agent. Antifungal agent 32 inhibits Candida albicans filamentation and biofilm formation. Antifungal agent 32 inhibits the morphological switching of Candida albicans and its adherence to epithelial cells. Antifungal agent 32 can be used for Candida albicans infections research .

HY-125152

Candicidin D CndD	Antibiotic Fungal	Infection
Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.

HY-P10604

SP2	Antibiotic Bacterial	Others
SP2 is a 14-amino acid long active peptide that can induce growth arrest in MTLa cells of the mating type locus of Candida albicans .

HY-149822

Antifungal agent 51	Fungal	Infection
Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity .

HY-121169

Amorolfine Ro 14-4767; Ro 14-4767/000	Fungal	Infection
Amorolfine (Ro 14-4767) is an antifungal agent. Amorolfine ameliorates the onychomycosis through inhibition of ergosterol biosynthesis. Amorolfine inhibits Candida albicans with a MIC of 0.404 µg/mL .

HY-N14922

Nikkomycin Lx	Antibiotic Bacterial	Infection
Nikkomycin Lx is an antibiotic that can be extracted from Streptomyces tendae TU901. Nikkomycin Lx exhibits anti-Candida Albicans activity and can be utilized in relevant research .

HY-N14923

Nikkomycin Lz	Fungal	Infection
Nikkomycin Lz is a nucleoside peptide antifungal compound isolated from genetically engineered Streptomyces tendae TU901. Nikkomycin Lz has antifungal activity against Candida albicans .

HY-164620

Antifungal agent 112	Fungal	Infection
Antifungal agent 112 (Compound 1e) exhibits antifungal activity against Candida albicans, Aspergillus niger and Aspergillus fumigatus with MIC of 0.0024, 0.0022 and 0.0028 M, respectively .

HY-136764

CYP51-IN-14	Fungal	Infection
CYP51-IN-2 (compound 1n), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC₈₀ of 1 μg/mL for Microsporum gypseum and Candida albicans .

HY-136759

CYP51-IN-9	Fungal	Infection
CYP51-IN-2 (compound 1i), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC₈₀ of 62.5 for Microsporum gypseum and Candida albicans .

HY-136762

CYP51-IN-12	Fungal	Infection
CYP51-IN-2 (compound 1l), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC₈₀ of 15.6 ng/mL for Microsporum gypseum and Candida albicans .

HY-136754

CYP51-IN-4	Fungal	Infection
CYP51-IN-2 (compound 1d), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC₈₀ of 15.6 ng/mL for Microsporum gypseum and Candida albicans .

HY-120432

CaMdr1p-IN-1	Fungal ATP-binding cassette (ABC) transporters	Infection
CaMdr1p-IN-1 (Compound A) is an inhibitor for the major facilitator superfamily transporter CaMdr1p. CaMdr1p-IN-1 exhibits chemosensitizing efficacy. CaMdr1p-IN-1 synergizes with Fluconazole (HY-B0101), that inhibits CaMdr1p overexpressing Candida albicans with MIC of 10 μM .

HY-136763

CYP51-IN-13	Fungal	Infection
CYP51-IN-2 (compound 1m), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC₈₀s of 62.5 and 250 ng/mL for Microsporum gypseum and Candida albicans, respectively .

Cat. No.	Product Name	Type

HY-126389

Chitin, from crab carapace (powder),biomedical research grade

Biochemical Assay Reagents

Chitin, from crab carapace (powder),biomedical research grade is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from crab carapace (powder),biomedical research grade is found in the exoskeleton of crabs. Chitin, from crab carapace (powder),biomedical research grade inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace (powder),biomedical research grade exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace (powder),biomedical research grade can be used in the research of gastric ulcer and candidiasis .

HY-P3466

Nisin Z	Biochemical Assay Reagents
Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans .

HY-126389B

Chitin, from shrimp shells (chitinase substrate)

Biochemical Assay Reagents

Chitin, from shrimp shells (chitinase substrate) serves as a substrate for chitinase. Chitin, from shrimp shells (chitinase substrate) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (chitinase substrate) is found in the exoskeleton of crabs. Chitin, from shrimp shells (chitinase substrate) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (chitinase substrate) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (chitinase substrate) can be used in the research of gastric ulcer and candidiasis .

HY-Y0248

(E,E)-Farnesol trans,trans-Farnesol; (2E,6E)-Farnesol	Biochemical Assay Reagents
(E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness .

HY-126389C

Chitin, from crab carapace

Biochemical Assay Reagents

Chitin, from crab carapace is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from crab carapace is found in the exoskeleton of crabs. Chitin, from crab carapace inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace can be used in the research of gastric ulcer and candidiasis .

HY-W039915

Allyl α-D-galactopyranoside

Biochemical Assay Reagents

Allyl α-D-galactopyranoside is an α-galactoside and acceptor/donor substrate for transgalactosylation reactions. Allyl α-D-galactopyranoside acts as an acceptor substrate in α-galactosidase-catalyzed transgalactosylation, and serves as a donor substrate to form longer α-galactosyl-containing oligosaccharides. Allyl α-D-galactopyranoside serves as a model compound for investigating the catalytic mechanism and substrate specificity of glycoside hydrolases and glycosyltransferases .

HY-126389A

Chitin, from shrimp shells (powder)

Biochemical Assay Reagents

Chitin, from shrimp shells (powder) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (powder) is found in the exoskeleton of crabs. Chitin, from shrimp shells (powder) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (powder) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (powder) can be used in the research of gastric ulcer and candidiasis .

HY-Y0248R

(E,E)-Farnesol (Standard)

trans,trans-Farnesol (Standard); (2E,6E)-Farnesol (Standard)

Biochemical Assay Reagents

(E,E)-Farnesol (Standard) (trans,trans-Farnesol (Standard)) is the analytical standard of (E,E)-Farnesol (HY-Y0248). This product is intended for research and analytical applications. (E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness .

Cat. No.	Product Name	Target	Research Area

HY-P10408

Candidalysin	EGFR MMP Calcium Channel NOD-like Receptor (NLR) ERK p38 MAPK	Infection Inflammation/Immunology
Candidalysin is a cytolytic peptide toxin secreted by the fungus Candida albicans. Candidalysin drives epithelial immune responses by activating the EGFR-MAPK signaling pathway, inducing MMP expression and calcium influx, and regulating the c-Fos transcription factor and MKP1 via p38 MAPK and ERK1/2 respectively. Candidalysin is essential for mucosal and systemic infections, activating NLRP3 to promote inflammatory responses, neutrophil recruitment, and Th17 immunity. Candidalysin activates LDH causing membrane damage and exhibiting cytotoxicity

HY-148690

L18-MDP	Bacterial Fungal	Infection
L18-MDP is a derivative of muramyl dipeptide, an antibacterial agent. L18-MDP has antibacterial activity and has potential applications in bacterial and fungal infections .

HY-P3466

Nisin Z	Bacterial Fungal	Infection Inflammation/Immunology
Nisin Z is an antimicrobial and anti-inflammatory peptide. Nisin Z is effective against Gram-positive bacteria and fungi, such as C. albicans .

HY-P10304

Cyclo(Arg-Pro) Cyclo(Pro-Arg)	Fungal	Others
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .

HY-105048

Omiganan 2 Publications Verification	Bacterial	Infection
Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne .

HY-129724A

α-MSH (11-13) acetate ACTH-(11-13) acetate; Lys-Pro-Val acetate; H-Lys-Pro-Val-OH acetate	Melanocortin Receptor NF-κB Bacterial Interleukin Related Apoptosis	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (11-13) (ACTH-(11-13)) acetate is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) acetate exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) acetate also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) acetate can be used in research related to traumatic brain injury, fever, and bacterial infections .

HY-106228

HLF1-11	Fungal Bacterial Glutathione Peroxidase	Infection
HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses .

HY-P2124

Cyclo(L-Trp-L-Trp)	Antibiotic Bacterial	Infection
Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research .

HY-P1629

Temporin A	Bacterial Fungal Antibiotic	Infection
Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans) .

HY-P2148

P-113	Bacterial Antibiotic	Infection Inflammation/Immunology
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans .

HY-P10304A

Cyclo(Arg-Pro) TFA Cyclo(Pro-Arg) TFA	Fungal	Infection
Cyclo (Arg-Pro) TFA is a chitinase inhibitor. Cyclo (Arg-Pro) TFA disrupts cell separation and morphological transition of yeast by inhibiting chitinase activity. Cyclo (Arg-Pro) TFA prevents cell separation of Saccharomyces cerevisiae, leading to the formation of grape-like cell clusters, without inhibiting cell growth. Cyclo (Arg-Pro) TFA blocks the morphological transition of Candida albicans from yeast form to hyphal form, without inhibiting cell growth .

HY-129724

α-MSH (11-13) ACTH-(11-13); Lys-Pro-Val; H-Lys-Pro-Val-OH	Melanocortin Receptor Bacterial NF-κB Apoptosis Interleukin Related	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (11-13) (ACTH-(11-13)) is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) can be used in research related to traumatic brain injury, fever, and bacterial infections .

HY-P10304C

Cyclo(Pro-dArg)	Fungal	Infection
Cyclo(Pro-dArg) is an inhibitor of chitinase. Cyclo(Pro-dArg) inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Pro-dArg) inhibits the transition of Candida albicans from yeast to filamentous morphology.

HY-P11170

D-Cateslytin	Fungal	Infection
D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis .

HY-P5681

Human α-Defensin 6	Bacterial	Infection Inflammation/Immunology
Human α-Defensin 6, a 32-residue cysteine-rich peptide, can inhibit bacterial invasion and contribute to the mucosal immunity. Human α-Defensin 6 forms ordered self-assembly fibrils and nanonets that surround and entangle bacteria after stochastic binding to bacterial surface proteins. Human α-Defensin 6 also inhibits C. albicans biofilm formation .

HY-P5640

Tritrpticin	Bacterial Parasite	Infection
Tritrpticin is a porcine-derived antimicrobial peptide with properties such as membrane disruption and hemolysis. Tritrpticin disrupts the cell membranes of bacteria, fungi and Jurkat T cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against Trichomonas vaginalis, reduces plasma endotoxin and inflammatory cytokine levels, restricts bacterial growth in blood and visceral tissues, decreases the mortality rate of septic shock in rats and enhances the therapeutic effect of ertapenem. Tritrpticin exhibits selective cytotoxicity against Jurkat T cell leukemia cells, while showing low toxicity to normal peripheral blood mononuclear cells and red blood cells, and can serve as a template for antimicrobial peptide design. Tritrpticin can be applied to research related to bacterial infections, fungal infections, trichomoniasis, septic shock and leukemia .

HY-P10603

SP1	Antibiotic Bacterial	Infection
SP1 is an α-peptide encoded by the mating pheromone MFα1 gene in Candida albicans, which can induce cell growth arrest at the mating type locus MTLa in Candida albicans. SP1 can be used in the study of the prevention and treatment of Candida albicans infection .

HY-P11114

Periplanetasin-4	Bacterial p38 MAPK Reactive Oxygen Species (ROS) Apoptosis Caspase	Infection Inflammation/Immunology
Periplanetasin-4 is an antimicrobial peptide that can be derived from the American cockroach (Periplaneta americana). Periplanetasin-4 reduces cell rounding and apoptosis. Periplanetasin-4 blocks Clostridium difficile toxin A-induced ROS production and the activation of downstream p38 MAPK and p21. Periplanetasin-4 significantly increases mitochondrial calcium level, reduces DPH fluorescence intensity and vacuolar dysfunction in Candida albicans ATCC 90028 cells. Periplanetasin-4 significantly ameliorates toxin A-induced mucosal damage in the mouse gut. Periplanetasin-4 can be used for the study of colitis .

HY-P2313

Human β-defensin-2 HβD-2	Antibiotic Bacterial	Infection
Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus . Human β-defensin-2 can be used for the study of colitis .

HY-P11191

AR-23	Bacterial	Infection
AR-23 is a melittin-related antimicrobial peptide that can be isolated from Rana tagoi. AR-23 exhibits broad-spectrum growth inhibitory activity against aerobic bacteria, the opportunistic yeast pathogen Candida albicans and clinical isolates of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). AR-23 can be used for antimicrobial research .

HY-P10996

Corticostatin, human TFA Human Neutrophil Peptide-4 TFA	Bacterial SARS-CoV	Infection
Corticostatin, human (Human Neutrophil Peptide-4) TFA is an antimicrobial peptide with demonstrated antiviral activity. Corticostatin, human TFA can kill Escherichia coli, Streptococcus faecalis, and Candida albicans. Corticostatin, human (HNP-4) TFA is more bactericidal against Gram-negative bacteria than any of HNP-1-3. Corticostatin, human TFA can be isolated from the azurophil granule fraction of discontinuous Percoll gradients .

HY-P5565

RP-1	Bacterial	Infection Cancer
RP-1 is an antimicrobial peptide, and is active against S. aureus, S. typhimurium, E. coli, and C. albicans .

HY-P11102

Temporin-SHa	Bacterial Fungal HIV Parasite	Infection Cancer
Temporin-Sha is an antibacterial peptide with extensive biological activity. Temporin-Sha exhibits broad-spectrum antibacterial activity (e.g., against L. ivanovii, MIC = 6.25 μM), and is effective against Gram-negative bacteria (such as Escherichia coli, MIC = 10 μM), including drug-resistant strains (such as Methicillin (HY-121544)-resistant Staphylococcus aureus). Temporin-Sha also has inhibitory effects on Candida albicans (MIC = 25 μM), Saccharomyces cerevisiae (MIC = 12 μM), the pre-flagellated and non-flagellated forms of Leishmania infantum (IC₅₀ = 5-20 μM), and Trypanosoma cruzi (IC₅₀ = 17 μM). Temporin-Sha exhibits antiviral activity against HSV-1 and has anti-cancer effects (cytotoxicity against breast cancer cells MCF-7 and lung cancer cells H460, etc.) .

HY-P5720

Peptide 5e	Bacterial	Infection
Peptide 5e is an antimicrobial peptide. Peptide 5e inhibits E. coli, S. aureus, and C. albicans with MIC values of 30, 5, 25 μg/mL respectively .

HY-P10604

SP2	Antibiotic Bacterial	Others
SP2 is a 14-amino acid long active peptide that can induce growth arrest in MTLa cells of the mating type locus of Candida albicans .

HY-P11171

Cysteine proteinase inhibitor peptide	Peptides	Others
Cysteine proteinase inhibitor peptide is a peptide that can be isolated form the culture media of Candida albicans with a molecular weight of 15 kDa and a PI of 4.9. Cysteine proteinase inhibitor peptide exhibits stability under both high temperature and a broad pH range .

HY-P11091

PA2-GNU7	Bacterial	Infection
PA2-GNU7 is an antimicrobial peptide (AMP). PA2-GNU7 exhibits potent antimicrobial activity with minimal inhibitory concentration (MIC) against P. aeruginosa, E. coli, S. typhimurium, S. aureus, and C. albicans are 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM, respectively. PA2-GNU7 rapidly and selectively kills Pseudomonas aeruginosa without affecting other commensal bacteria. PA2-GNU7 significantly improves survival of mice infected with P. aeruginosa. PA2-GNU7 can be used for the research and development of therapeutic agents against MDR Pseudomonas aeruginosa infections .

HY-P3916

GVLSNVIGYLKKLGTGALNAVLKQ	Bacterial	Infection Inflammation/Immunology
GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide with 24-amino acid. GVLSNVIGYLKKLGTGALNAVLKQ can potentially form α-helix. GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) has activity against Gram-negative, Gram-positive bacteria and the yeast Candida albicans .

HY-P10538

Balteatide	Bacterial Fungal	Infection
Balteatide is an antimicrobial peptide, which can be found in skin secretion of Phyllomedusa baltea. Balteatide inhibits the gram-positive Staphylococcus aureus (MIC=435 μM), the gram-negative Escherichia coli (MIC=109 μM), and Candida albicans (MIC=27 μM). Balteatide lacks hemolytic activity (at 512 mg/L) and myotropic activity .

HY-P11021

ToAP2	Fungal Antibiotic	Infection
ToAP2 is a potent antimicrobial peptide. ToAP2 affects C. albicans membrane permeability and produces changes in fungal cell morphology .

HY-P11021A

ToAP2 TFA	Fungal Antibiotic	Infection
ToAP2 TFA is a potent antimicrobial peptide. ToAP2 TFA affects C. albicans membrane permeability and produces changes in fungal cell morphology .

HY-P5648

PhD2	Bacterial	Infection
PhD2 is an antimicrobial peptide derived from monkey white blood cells. PhD2 has activity against bacteria and fungus Candida albicans .

HY-P5647

PhD1	Bacterial	Infection
PhD1 is an antimicrobial peptide derived from monkey white blood cells. PhD1 has activity against bacteria and fungus Candida albicans .

HY-P5649

PhD3	Bacterial	Infection
PhD3 is an antimicrobial peptide derived from monkey white blood cells. PhD3 has activity against bacteria and fungus Candida albicans .

HY-P5569

SP-B peptide	Fungal	Infection
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus

HY-P5651

PhD4	Bacterial	Infection
PhD4 is an antimicrobial peptide derived from monkey white blood cells. PhD4 has activity against bacteria and fungus Candida albicans .

HY-P0068

Aminocandin HMR 3270; IP960; NXL201	Fungal	Infection
Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp. .

HY-P5663

Bombinin H-BO1	Bacterial	Infection
Bombinin H-BO1 is an antimicrobial peptide derived from toad Bombina orientalis skin secretions. Bombinin H-BO1 is active against Candida albicans, and the MIC value is 256 mg/L .

HY-P5665

Bombinin-BO1	Peptides	Infection
Bombinin-BO1 is an antimicrobial peptide derived from toad Bombina orientalis skin secretions. Bombinin-BO1 is active against E. coli, S. aureus and Candida albicans, the MIC values are 64, 64, 128 mg/L, respectively .

HY-P5625

ROAD-1	Bacterial	Infection
ROAD-1 is an oral mucosal α-defensin of Rhesus Macaque. ROAD-1 is active against S. aureus, E. coli, and C. albicans .

HY-P5655

Maximin H4	Bacterial	Infection
Maximin H4 is an antimicrobial peptide derived from the skin secretions of Chinese red belly toad Bombina maxima. Maximin H4 has activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010 and Candida albicans ATCC2002, the MIC values are 12, 6, 12, 6 μg/ml, respectively .

HY-P5618

Maximin H2	Bacterial	Infection
Maximin H2 is an antimicrobial peptide derived from the skin secretions of Chinese red belly toad Bombina maxima. Maximin H2 has activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010 and Candida albicans ATCC2002, the MIC values are 20, 2, 4, 2 μg/ml, respectively .

HY-P5619

Maximin H3	Bacterial	Infection
Maximin H3 is an antimicrobial peptide derived from the skin secretions of Chinese red belly toad Bombina maxima. Maximin H3 has activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010 and Candida albicans ATCC2002, the MIC values are 20, 10, 20, 5 μg/ml, respectively .

HY-P5616

Maximin H1	Bacterial	Infection
Maximin H1 is an antimicrobial peptide derived from the skin secretions of Chinese red belly toad Bombina maxima. Maximin H1 has activity against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus CMCCB1010 and Candida albicans ATCC2002, the MIC values are 9, 4.5, 9, 4.5 μg/ml, respectively .

HY-P10795

NK-2 Antibiotic NK 2	Parasite Bacterial Fungal	Infection
NK-2 (Antibiotic NK 2), a shortened linear amphipathic NK-Lysin analog (comprising residues 39 to 65 of NK-lysin), is an antimicrobial peptide that exhibits potent activities against trypanosoma cruzi, Candida albicans, gram-positive and gram-negative bacteria. NK-2 can kill trypanosomes residing inside the human glioblastoma cell line 86HG39, left the host cells apparently unharmed .

HY-P10540

Pantinin-2	Bacterial	Infection
Pantinin-2 is a cysteine-free toxic peptide found in the emperor scorpion (paninus imperator). Pantinin-2 has high activity against Gram-positive bacteria but weak activity against Gram-negative bacteria. Pantinin-2 also exhibits activity against Candida tropicalis and has relatively mild hemolytic activity against human erythrocytes. Pantinin-2 can be used in the development of antimicrobial drugs for drug-resistant pathogens .

HY-P2124R

Cyclo(L-Trp-L-Trp) (Standard)	Reference Standards Antibiotic Bacterial	Infection
L-Isoleucine (Standard) is the analytical standard of L-Isoleucine. This product is intended for research and analytical applications. L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro .

HY-P5730

Peptide 5g	Bacterial	Infection
Peptide 5g is an antimicrobial peptide. Peptide 5g inhibits E. coli, S. aureus, and C. albicans with MIC values of 30, 10, 12.5 μg/mL respectively .

HY-121982

Cyclo(L-Phe-L-Val)	Fungal	Infection
Cyclo(L-Phe-L-Val) is a potent inhibitor of enzymes isocitrate lyase (ICL) (IC₅₀=27 μg/mL). cyclo(L-Phe-L-Val) inhibits the gene transcription of ICL in C. albicans under C₂-carbon-utilizing conditions .

HY-P5613

XT-1	Bacterial	Infection
XT-1 is an antimicrobial peptide derived from skin secretions of Xenopus tropicalis. XT-1 has strong activity against S.aureus, E.coli and C.albicans, the vaule of MIC are 5, 6, 50 μM , respectively .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992076

*Anti-Candida* auris β-1, 3 glucans Antibody (2G8)**	TGF-β Receptor TGF-beta/Smad Cholinesterase (ChE) Fungal	Infection Cancer
Anti-Candida auris β-1,3-glucans Antibody (2G8) is an antibody targeting Candida auris β-1,3-glucans, and also acts as an inhibitor of AChE and TGF-β receptor 2. Anti-Candida auris β-1,3-glucans Antibody (2G8) also targets fungal cell wall components, effectively inhibits fungal growth and interferes with capsule formation, thereby significantly reducing the fungal load in mouse tissues. Anti-Candida auris β-1,3-glucans Antibody (2G8) not only blocks TGF-β receptor binding to inhibit the Smad signaling pathway, reduces fibroblast activation and collagen deposition, but also induces epithelial differentiation of tumor cells and reduces pancreatic tumor metastasis. Anti-Candida auris β-1,3-glucans Antibody (2G8) specifically binds to the conserved N-linked glycoepitope on AChE to inhibit its activity without interfering with BChE, and can be used in studies of cryptococcosis and related tumor mechanisms .The isotype control is Human IgG1 kappa, Isotype Control (HY-P99001).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0248A

Farnesol 2 Publications Verification	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Plants Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants Antibiotic Endogenous Metabolite Bacterial
Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.

HY-12538

Graveoline Rutamine	Structural Classification Alkaloids Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants Source Classification	Apoptosis Autophagy Fungal Parasite Reactive Oxygen Species (ROS) Interleukin Related JAK STAT
Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury .

HY-N3307

(+)-Medioresinol 1 Publications Verification	Cardiovascular Disease Oleaceae Fraxinus mandshurica Rupr. Neurological Disease Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Source Classification	Bacterial Fungal Reactive Oxygen Species (ROS) Apoptosis MMP Interleukin Related PI3K Akt mTOR PPAR PGC-1α Pyroptosis
(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke .

HY-N2512

1-Monomyristin 1 Publications Verification	Infection Structural Classification Serenoa repens Classification of Application Fields Palmae Plants Disease Research Fields Steroids	Environmental Pollutants Endogenous Metabolite FAAH Autophagy Bacterial Fungal
1-Monomyristin acts as an insecticide, enzyme inhibitor, antibacterial and antifungal agent, with an IC₅₀ of 18 μM against rat FAAH and an IC₅₀ of 32 μM against rat MAGL. 1-Monomyristin inhibits 2-oleoylglycerol hydrolysis via MAGL. 1-Monomyristin suppresses the growth of Staphylococcus aureus, Aggregatibacter actinomycetemcomitans and Candida albicans. 1-Monomyristin is lethal to brine shrimp . 1-Monomyristin exhibits marginal cytotoxicity against prostate cancer cells. 1-Monomyristin is applicable to research related to bacterial infections, fungal infections, renal cancer, prostate adenocarcinoma and pancreatic cancer .

HY-108485

Damnacanthal	Infection Quinones Monophenols Classification of Application Fields Anthraquinones Morinda citrifolia Linn. Rubiaceae Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Src Apoptosis Fungal
Damnacanthal is an anthraquinone isolated from the root of Morinda citrifolia. Damnacanthal is a highly potent, selective inhibitor of p56 ^lck tyrosine kinase activity. Natural Damnacanthal inhibits p56 ^lck autophosphorylation and phosphorylation of exogenous substrates with IC₅₀s of 46 nM and 220 nM, respectively. Damnacanthal is a potent inducer of apoptosis with anticancer activity. Damnacanthal also has antinociceptive, anti-inflammatory effects in mice and anti-fungal activity against **Candida albicans** .

HY-N7626

Eleutherol	Infection Monophenols Iridaceae Classification of Application Fields Phenols Eleutherine plicata Herb. Plants Disease Research Fields Source Classification	Fungal Glycosidase
Eleutherol is a naphthalene isolated from E. americana with antifungal activities . Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL . Eleutherol inhibits α-glucosidase function with an IC₅₀>1.00 mM .

HY-N12717

Casuarinin	Terminalia arjuna (Roxb. ex DC.) Wight & Arn. Structural Classification Combretaceae Phenols Polyphenols Plants Source Classification	PAK FASTK HSP p38 MAPK NF-κB NO Synthase COX HSV Caspase TNF Receptor Fungal Apoptosis
Casuarinin is an orally active antiproliferative, anti-inflammatory, antifungal, virucidal and gastroprotective agent. Casuarinin upregulates the expression of p21/WAF1, Fas/APO‑1, mFasL, sFasL and HSP‑70, arrests cell cycle, induces apoptosis and inhibits cancer cell proliferation. Casuarinin inhibits TNF‑α-induced phosphorylation of MAPK and activation of NF‑κB, downregulates the expression of iNOS, NF‑κB, COX‑2 and ICAM‑1, and reduces the production of proinflammatory mediators. Casuarinin attenuates ethanol-induced activation of caspase‑3 and elevation of TNF‑α, inhibits the growth of **Candida albicans, and inhibits HSV‑2**. Casuarinin can be used in research related to mammary adenocarcinoma, inflammatory skin diseases, gastric ulcers, candidiasis and herpes simplex virus infections .

HY-N6924

Zingibroside R1 1 Publications Verification	Infection Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Saccharides Araliaceae Source Classification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of **Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1**-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

HY-N3138

Ombuoside	Infection Flavonols Flavonoids Classification of Application Fields Cucurbitaceae Phenols Polyphenols Plants Gynostemma pentaphyllum (Thunb.) Makino Disease Research Fields Source Classification	Bacterial Apoptosis Reactive Oxygen Species (ROS) ERK JNK Caspase SOD Fungal
Ombuoside has antioxidant properties, inhibiting ROS production and apoptosis. Ombuoside exerts neuroprotective effects through the ERK-JNK-caspase-3 system. Ombuoside promotes Dopamine biosynthesis through TH and CREB activation. Ombuoside exhibits antimicrobial activity against several Gram-positive and Gram-negative bacteria, as well as Candida albicans

HY-W357140

β-Phenylethyl β-D-glucoside Phenylethyl β-D-glucopyranoside	Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides Source Classification	Fungal
β-Phenylethyl β-D-glucoside (Phenylethyl β-D-glucopyranoside) (Compound 7), a phenolic compounds, is an antifungal agent. β-Phenylethyl β-D-glucoside can be isolated from the leaves of Piper crocatum. β-Phenylethyl β-D-glucoside has antifungal activity against Candida albicans. β-Phenylethyl β-D-glucoside can be used for fungal infections research .

HY-B0101R

Fluconazole (Standard) UK-49858 (Standard)	Microorganisms Source Classification	Reference Standards Fungal Antibiotic Bacterial
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-N7107

Fenchyl alcohol	Infection Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	Environmental Pollutants Fungal
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-N3968

Goniothalamin GTN; (R)-(+)-Goniothalamin	Structural Classification Natural Products Lythraceae Plants Lythrum salicaria L. Source Classification	Apoptosis Insecticide Bacterial Fungal Reactive Oxygen Species (ROS)
Goniothalamin (GTN) is a styryl lactone. Goniothalamin exhibits insecticidal, anti-tumor and antibacterial activities. Goniothalamin induces cell cycle arrest and apoptosis in tumor cells. Goniothalamin acts as a larvicide against Culex quinquefasciatus larvae and as a cytotoxin against brine shrimp larvae. Goniothalamin functions as an antibacterial agent against Gram-positive and Gram-negative bacteria, and also acts as an antifungal agent against pathogens including Candida albicans, Trichophyton rubrum and Trichophyton mentagrophytes. Goniothalamin is applicable to research related to breast cancer, lymphatic filariasis, bacterial infections and fungal infections .

HY-N6952R

Geraniol (Standard) 2 Publications Verification	Infection Structural Classification other families Classification of Application Fields Terpenoids Plants Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Fungal Endogenous Metabolite
Geraniol (Standard) is the analytical standard of Geraniol. This product is intended for research and analytical applications. Geraniol, an olefinic terpene, was found to inhibit growth of Candida albicans and Saccharomyces cerevisiae strains .

HY-N8540

Ilicicolin H	Natural Products Microorganisms Source Classification	Phosphoglycerate Kinase (PGK) Fungal Apoptosis
Ilicicolin H is a selective and non-ATP-competitive phosphoglycerate kinase 1 (PGK1) (IC₅₀ = 9.02 μM) and mitochondrial cytochrome bc1 reductase (IC₅₀ = 2-3 ng/mL) inhibitor. Ilicicolin H directly binds to PGK1 with K_D of 60 μM .Ilicicolin H can inhibit cell proliferation and induce apoptosis. Ilicicolin H can inhibit the lactate production and glucose uptake of hepatocellular carcinoma (HCC) cells. Ilicicolin H has a broad antifungal spectrum including C. albicans, Cryptococcus and A. fumigatus. Ilicicolin H can be used for the researches of cancer and infection, such as hepatocellular carcinoma (HCC) and C. albicans infection .

HY-N11709

Theasaponin E1	Triterpenes Structural Classification Terpenoids Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Apoptosis VEGFR ATM/ATR PTEN Akt mTOR HIF/HIF Prolyl-Hydroxylase NF-κB Notch Cholinesterase (ChE) Amyloid-β γ-secretase Ferroptosis Fungal
Theasaponin E1 is an orally effective tea saponin. Theasaponin E1 inhibits the proliferation of cancer cells by activating apoptosis. Theasaponin E1 inhibits angiogenesis in ovarian cancer cells and HUVECs by reducing the expression of VEGF. Theasaponin E1 upregulates the phosphorylation level of ATM protein and the expression level of PTEN protein in cancer cells, decreases the phosphorylation levels of Akt, mTOR, p70S6K and 4E-BP1 proteins, downregulates the expression of HIF-1α and NF-κB, and reduces the protein expression of Notch ligands Dll4 and Jagged1. Theasaponin E1 exerts neuroprotective effects by inhibiting the activity of acetylcholinesterase, activating α-secretase and neprilysin, reducing the concentration of Aβ, and inhibiting the activities of β-secretase and γ-secretase. Theasaponin E1 exhibits toxic effects on cancer cells and quinone reductase-inducing activity, and inhibits tumor growth in vivo. Theasaponin E1 induces ferroptosis in Pomacea canaliculata by synergistically disrupting cholesterol homeostasis and sphingolipid metabolism. Theasaponin E1 possesses anti-biofilm activity against Candida albicans. Theasaponin E1 can be used in the research of ovarian cancer, obesity, Alzheimer's disease and fungal infections .

HY-N10113

Verrucarin J 1 Publications Verification Muconomycin B	Infection Natural Products Microorganisms Classification of Application Fields Marine algae Marine natural products Disease Research Fields Source Classification	Apoptosis Arenavirus Fungal Antibiotic Reactive Oxygen Species (ROS)
Verrucarin J (Muconomycin B) is a metabolite of the Myrothecium fungus family. Verrucarin J generates reactive oxygen species (ROS) and induces apoptosis of cancer cell lines, such as A549, HCT 116 and SW-620 cells. Verrucarin J shows activities against Candida albicans and Mucor miehei. Verrucarin J inhibits arenavirus Junin (JUNV) yield with an IC₅₀ of 1.2 ng/mL .

HY-Y0248AR

Farnesol (Standard) 2 Publications Verification	Structural Classification other families Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Bacterial Antibiotic
Farnesol (Standard) is the analytical standard of Farnesol. This product is intended for research and analytical applications. Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans, and has the activity in inhibiting bacteria.

HY-N4164

Schinifoline	Zanthoxylum bungeanum Maxim. Alkaloids Classification of Application Fields Rutaceae Quinoline Alkaloids Plants Disease Research Fields Source Classification Cancer	Fungal Apoptosis
Schinifoline is a 4-quinolinone found in Zanthoxylum schinifolium. Schinifoline can inhibit cancer cells proliferation, cause G2/M phase arrest and induce apoptosis. Schinifoline can improve radiosensitizing effect of cancer cells. Schinifoline shows anti-fungal activity. Schinifoline can be used for the researches of cancer and infection, such as lung cancer and C. albicans infection .

HY-118401

Mansonone E	Malvaceae Mansonia gagei J.R.Drumm. Quinones Structural Classification Plants Naphthalene Quinones Source Classification	Fungal Bacterial Herbicide
Mansonone E (Compound 5) is a pesticide. Mansonone E can be isolated from heartwood of Mansonia gagei. Mansonone E has significant antifungal activity against Cladosporium cucumerinum, Candida albicans and Phytophthora parasitica. Mansonone E has potent antibacterial activity with MIC₅₀s of both 7.8 μg/mL for Xanthomonas oryzae pv. oryzae and X. oryzae pv. Oryzicola. Mansonone E also has antifeedant and herbicidal activities .

HY-N16392

14-epi-Berkeleylactone F	Natural Products Microorganisms Source Classification	Endogenous Metabolite
14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells .

HY-129260

Kanosamine 3-Amino-3-deoxyglucose	Microorganisms Source Classification	Fungal
Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic against Saccharomyces cerevisiae and human pathogenic fungi Candida albicans. Kanosamine exhibits antifungal activity through inhibition of cell wall synthesis and inhibition of GlcN-6-P synthase with phosphorylated kanosamine-6-phosphate in cytoplasma .

HY-135445

Prolylrapamycin 21-Norrapamycin	Natural Products Microorganisms Source Classification	Fungal
Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin (HY-10219). Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL .

HY-N2105

(-)-Dicentrine L-Dicentrine	Structural Classification Alkaloids Aporphine Alkaloids Plants Menispermaceae Source Classification Stephania sinica Diels	Fungal Bacterial
(-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans .

HY-N15640

Filiformin (-)-Filiformin	Structural Classification Terpenoids Marine algae Sesquiterpenes Marine natural products Source Classification	Bacterial
Filiformin ((-)-Filiformin) is a sesquiterpene compound that can be isolated from Laurencia filiformis forma heteroclada. Filiformin exhibits certain cytotoxicity against P388 and BSC-1 cells. Filiformin has antimicrobial activity against Bacillus subtilis, Trichophyton mentagrophytes and Candida albicans. In addition, Filiformin can inhibit oxygen uptake in isolated rat liver mitochondria at a concentration of 150 μM .

HY-N11772

Mutanocyclin	Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

HY-N3171

Nortrachelogenin (-)-Wikstromol; (-)-Nortrachelogenin	Natural Products other families Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Cancer Source Classification	Apoptosis
Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans .

HY-142003

27-O-Demethylrapamycin	Natural Products Microorganisms Source Classification	Fungal
27-O-Demethylrapamycin, a Rapamycin (HY-10219) derivative, is an antifungal agent. 27-O-Demethylrapamycin inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum .

HY-N3574

Chloramultilide B	Structural Classification Chloranthus serratus (Thunb.) Roem. et Schult. Terpenoids Sesquiterpenes Chloranthaceae Plants Source Classification	Fungal
Chloramultilide B is a lindenane dimer that can be isolated from Chloranthus serratus. Chloramultilide B has inhibitory activities against Candida albicans and C.parapsilosis with a MIC value of 0.068 μM .

HY-P2450

Leucinostatin A Antibiotic P168	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Fungal Antibiotic
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-135422

Nidulin Methylustin	Natural Products Microorganisms Source Classification	Bacterial Fungal
Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp .

HY-N2512R

1-Monomyristin (Standard)	Structural Classification Serenoa repens Palmae Plants Steroids	Reference Standards FAAH Bacterial Fungal Endogenous Metabolite Autophagy
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans .

HY-128478

Sordarin	Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal
Sordarin (Compound 1) is an antifungal agent targeting Elongation factor 2 (EF2) with a tetracyclic diterpene core including a norbornene system. Sordarin can be isolated from the fungus Sordaria araneosa. Sordarin has potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. Sordarin prevents the translocation of the ribosome along mRNA during elongation of the emerging polypeptide chain, inhibiting protein synthesis in fungi by stabilizing the ribosome/EF2 complex .

HY-N16444

Sporminarin B	Natural Products Microorganisms Source Classification	Fungal Bacterial
Sporminarin B is an antibacterial and antifungal agent. Sporminarin B exhibits inhibitory activity against microorganisms such as Candida albicans and Staphylococcus aureus .

HY-N14922

Nikkomycin Lx	Microorganisms Ketones, Aldehydes, Acids Source Classification	Antibiotic Bacterial
Nikkomycin Lx is an antibiotic that can be extracted from Streptomyces tendae TU901. Nikkomycin Lx exhibits anti-Candida Albicans activity and can be utilized in relevant research .

HY-N14923

Nikkomycin Lz	Microorganisms Ketones, Aldehydes, Acids Source Classification	Fungal
Nikkomycin Lz is a nucleoside peptide antifungal compound isolated from genetically engineered Streptomyces tendae TU901. Nikkomycin Lz has antifungal activity against Candida albicans .

HY-N12606

Neodidymelliosides A	Microorganisms Saccharides Monosaccharides Source Classification	Fungal
Neodidymelliosides A (compound 1)It is a secondary metabolite of fungi and has a significant inhibitory effect on Staphylococcus aureus and Candida albicans biofilms. Neodidymelliosides AIt also has anti-cancer activity and can inhibit KB3.1 (cervix),PC-3 (prostate),MCF-7(breast),SKOV-3 (ovary),A431 (skin )and A549 (lung )Cell viability of cell lines .

HY-N13025

8-Acetylverrucarin L Verrucarin L acetate	Natural Products Microorganisms Source Classification	Fungal
8-Acetylverrucarin L (Verrucarin L acetate) is a mycotoxin, which exhibits antitumor and antimicrobial activities. 8-Acetylverrucarin L exhibits cytotoxicity to cancer cells HCT116 and A2780S, with IC₁₀₀ of 9.77 and 9.77 ng/mL. 8-Acetylverrucarin L exhibits antifungal activity against Saccharomyces cerevisiae, Candida albicans and Geotrichum candidum .

HY-N14960

Clavariopsin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic
Clavariopsin A is a cyclic depsipeptide antibiotic. Clavariopsin A shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 2, 4 μg/mL, respectively .

HY-N14961

Clavariopsin B	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic
Clavariopsin B is a cyclic depsipeptide antibiotic. Clavariopsin B shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 4, 4 μg/mL, respectively .

HY-N12264

Burnettramic acid A	Microorganisms Antibiotics Source Classification	Antibiotic Bacterial Fungal
Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC₅₀ of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC₅₀ of 13.8 μg/mL .

HY-N12230

Penicolinate B	Microorganisms Ketones, Aldehydes, Acids Source Classification	Bacterial Parasite Fungal
Penicolinate B is a picolinic acid derivative that can be isolated from Penicillium sp. Penicolinate B exhibits antimalarial activity (IC₅₀: 1.40 μg/mL), antitubercular activity (MIC: 25.0 μg/mL), activity against Bacillus cereus (IC₅₀: 25.0 μg/mL), and activity against Candida albicans (IC₅₀: 1.45 μg/mL). Penicolinate B also has certain cytotoxicity against cancer cells such as MCF-7, KB, and NCI-H187. Penicolinate B can be used in research on malaria, tuberculosis, bacterial/fungal infections and tumors .

HY-N7107R

Fenchyl alcohol (Standard)	Structural Classification Other Monoterpenes other families Terpenoids Plants Source Classification	Reference Standards Fungal
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer .

HY-N14018

Glidobactin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice .

HY-137794

Tetramethylkaempferol	Flavonoids Flavones Kaempferia parviflora Wall. ex Baker Plants Source Classification Zingiberaceae	Fungal
Tetramethylkaempferol is an antifungal agent. Tetramethylkaempferol shows antifungal activity against Candida albicansCandida albicans with an IC₅₀ value of 17.63 µg/mL .

HY-N14315

Ochracenomicin A	Quinones Microorganisms Anthraquinones Source Classification	Bacterial
Ochracenomicin A has a strong effect against Gram-positive bacteria (including MRSA strain), and also against Gram-negative bacteria and candida albicans .

HY-N13962

Bagremycin A	Natural Products Microorganisms Source Classification	Bacterial Fungal
Bagremycin A is found in the strain of Streptomyce sp. Tu 4128. Bagremycin A has weak activity against Gram-positive bacteria, Saccharomyces cerevisiae and Candida albicans .

HY-N14583

Glucoallosamidin A	Structural Classification Microorganisms Antibiotics Source Classification	Antibiotic Fungal
Glucoallosamidin A is a glycoside antibiotic that can inhibit Chitinase activity. Glucoallosamidin A can inhibit Candida albicans ATCC 10231 chitinase with an IC₅₀ of 3.4 μg/mL .

HY-W152146

Methylxanthoxylin	Monophenols Phenols Myrtaceae Syzygium aromaticum (L.) Merr. & L.M.Perry Plants Source Classification	Fungal
Methylxanthoxylin is a ketone that can be isolated from the leaves and bark of Acradenia Jianklinii . Methylxanthoxylin exhibited moderate antifungal activity against Candida albicans and Penicillium expansum .

HY-N14155

Epelmycin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Fungal
Epelmycin A has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin .

Species:	Human (1)
Tag:	His (2) Tag Free (1) Strep (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703504

	*FDH1 Protein, Candida* boidinii (C23S, C262A, His, Strep)** FDH; FDH3; Candida boidinii (Yeast)	Human	E. coli
	FDH1 protein serves as a catalyst in the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity represents the conclusive step in the methanol oxidation pathway within methylotrophic microorganisms. Beyond its involvement in methylotrophic organisms, FDH1 also plays a crucial role in non-methylotrophic organisms, where it contributes to the detoxification of exogenous formate. FDH1 Protein, Candida boidinii (C23S, C262A, His, Strep) is the recombinant Candida boidinii-derived FDH1, expressed by E. coli, with Strep, His labeled tag.

HY-P702119

	*FDH1 Protein, Candida* boidinii** FDH1; Formate dehydrogenase; FDH; NAD-dependent formate dehydrogenase	Others	E. coli
	FDH1 protein serves as a catalyst in the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity represents the conclusive step in the methanol oxidation pathway within methylotrophic microorganisms. Beyond its involvement in methylotrophic organisms, FDH1 also plays a crucial role in non-methylotrophic organisms, where it contributes to the detoxification of exogenous formate. FDH1 Protein, Candida boidinii is the recombinant FDH1 protein, expressed by E. coli , with tag free.

HY-P702120

	*FDH1 Protein, Candida* boidinii (His)** FDH1; Formate dehydrogenase; FDH; NAD-dependent formate dehydrogenase	Others	E. coli
	FDH1 protein serves as a catalyst in the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity represents the conclusive step in the methanol oxidation pathway within methylotrophic microorganisms. Beyond its involvement in methylotrophic organisms, FDH1 also plays a crucial role in non-methylotrophic organisms, where it contributes to the detoxification of exogenous formate. FDH1 Protein, Candida boidinii (His) is the recombinant FDH1 protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0101S

Fluconazole-d4
Fluconazole-d₄ is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-15660S

Efinaconazole-d4
Efinaconazole-d₄ is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .

HY-Y0248AS

(E,E)-Farnesol-d6
(E,E)-Farnesol-d₆ (trans,trans-Farnesol-d₆) is deuterium labeled (E,E)-Farnesol (HY-Y0248). (E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness .

HY-17395S

Terbinafine-d3 hydrochloride

Terbinafine-d₃ hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-B1290S2

2-Phenylethanol-d5

2-Phenylethanol-d₅ is the deuterium labeled 2-Phenylethanol . 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans . It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-17395AS

Terbinafine-d7
Terbinafine-d₇ is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a K_i of 30 nM . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria .

HY-B0101S1

Fluconazole-13C2,15N
Fluconazole-13C2,15N (UK-49858-13C2,15N) is the ¹³C and ¹⁵N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-B0852S

Tebuconazole-d9
Tebuconazole-d₉ is the deuterium labeled Tebuconazole. Tebuconazole is an agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively.

HY-B1290S

2-Phenylethanol-d4

2-Phenylethanol-d₄ is the deuterium labeled 2-Phenylethanol . 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans . It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-B1290S1

2-Phenylethanol-d9

2-Phenylethanol-d₉ is the deuterium labeled 2-Phenylethanol . 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans . It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-W716702

Aldox-d6

Aldox-d₆ (Lexamine M-13-d₆; MAPD-d₆) is the deuterium labeled Myristamidopropyl dimethylamine (HY-W099582). Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .

HY-W753345

2,6-Dichlorodiphenylamine-13C6

2,6-Dichlorodiphenylamine- ¹³C₆ (2,6-Dichloro-N-phenylaniline- ¹³C₆) is the ¹³C-labeled 2,6-Dichlorodiphenylamine (HY-W012126). 2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a?COX?inhibitor, with?IC₅₀s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.

HY-B0852S2

Tebuconazole-d6

Tebuconazole-d₆ is a deuterium labeled Tebuconazole (HY-B0852). Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC₅₀s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells .

HY-A0132S14

N-Acetyl-D-glucosamine-d3

N-Acetyl-D-glucosamine-d₃ (N-Acetyl-2-amino-2-deoxy-D-glucose-d₃) is deuterium labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits .

HY-B0518AS

Naftifine-d3 hydrochloride
Naftifine-d₃ (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .

HY-17395AS1

Terbinafine-d3

Terbinafine-d₃ (TDT 067-d₃) is deuterium labeled Terbinafine. Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a K_i of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W768347

Xylitol-13C5

Xylitol- ¹³C₅ (Xylite- ¹³C₅) is the ¹³C-labeled Xylitol (HY-N0538). Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

HY-W012444S

Glyceryl 1-monooctanoate-d15

Glyceryl 1-monooctanoate-d₁₅ is the deuterium labeled Glyceryl 1-monooctanoate (HY-W012444). Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria .

HY-W704402

Glyceryl 1-monooctanoate-d5

Glyceryl 1-monooctanoate-d₅ is the deuterium labeled Glyceryl 1-monooctanoate (HY-W012444). Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria .

HY-W724326

Tebuconazole-d4

Tebuconazole-d₄ is the deuterium labeled Tebuconazole (HY-B0852). Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC₅₀s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells .

HY-B0139AS1

Flucytosine-15N2 hydrochloride

Flucytosine- ¹⁵N₂ (5-Fluorocytosine- ¹⁵N₂) hydrochloride is the ¹⁵N-labeled Flucytosine hydrochloride (HY-B0139). Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells.

HY-B0518S1

Naftifine-d3
Naftifine-d₃ is the deuterium labeled Naftifine. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .

HY-B0518S3

Naftifine-13C,d3
Naftifine- ¹³C,d₃ is the ¹³C- and deuterium labeled Naftifine. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .

HY-17579S

Micafungin-d11 ammonium
Micafungin-d₁₁ ammonium (FK463-d₁₁ ammonium) is the deuterium labeled Micafungin ammonium. Micafungin (FK463) is an antifungal agent and can inhibit β-1,3-glucan synthase. Micafungin inhibits 1,3-β-glucan biosynthesis in fungal cell walls. Micafungin can be used for the research of fungal infection, such as candida infections and aspergillosis .

Cat. No.	Product Name		Classification

HY-W326159

Giparmen		Alkynes
Giparmen is an anti-tubercular agent. Giparmen is promising for research of fungal infections, particularly Candida .

Cat. No.	Product Name		Classification

HY-N0538

Xylitol Xylite		Fillers
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model .

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Candida albicans NCIM 3471

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