1. Anti-infection
  2. Fungal
  3. Rezafungin acetate

Rezafungin acetate (Synonyms: Biafungin acetate; CD101 acetate; SP-3025 acetate)

Cat. No.: HY-108009A Purity: 98.04%
Handling Instructions

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp..

For research use only. We do not sell to patients.

Rezafungin acetate Chemical Structure

Rezafungin acetate Chemical Structure

CAS No. : 1631754-41-0

Size Price Stock Quantity
5 mg USD 480 In-stock
Estimated Time of Arrival: December 31
10 mg USD 800 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1700 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4300 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].

In Vivo

Rezafungin acetate (Biafungin acetate) (1 mg/kg; i.p. once daily for 6 days) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C3H/HeN mice[1]
Dosage: 1 mg/kg
Administration: Intraperitoneal injection; once daily for 6 days
Result: Significantly reduced nuclei and asci burdens.
Molecular Weight

1285.44

Formula

C₆₅H₈₈N₈O₁₉

CAS No.

1631754-41-0

SMILES

O=C1N2[[email protected]]([[email protected]@H](O)[[email protected]@H](C)C2)([H])C(N[[email protected]]([[email protected]@H](C[[email protected]@H](C(N[[email protected]]([[email protected]](O)C)([H])C(N3[[email protected]](C[[email protected]@H](O)C3)([H])C(N[[email protected]]([[email protected]](O)[[email protected]](C4=CC=C(O)C=C4)O)([H])C(N[[email protected]@]1([H])[[email protected]](O)C)=O)=O)=O)=O)NC(C5=CC=C(C6=CC=C(C7=CC=C(OCCCCC)C=C7)C=C6)C=C5)=O)O)([H])OCC[N+](C)(C)C)=O.[O-]C(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 230 mg/mL (178.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7779 mL 3.8897 mL 7.7794 mL
5 mM 0.1556 mL 0.7779 mL 1.5559 mL
10 mM 0.0778 mL 0.3890 mL 0.7779 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5.75 mg/mL (4.47 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5.75 mg/mL (4.47 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5.75 mg/mL (4.47 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

RezafunginBiafunginCD101SP-3025CD 101CD-101SP3025SP 3025Fungallong-lastingechinocandinantifungalinfectionInhibitorinhibitorinhibit

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Product Name:
Rezafungin acetate
Cat. No.:
HY-108009A
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