1. Anti-infection
  2. Fungal
  3. Rezafungin acetate

Rezafungin acetate (Synonyms: Biafungin acetate; CD101 acetate; SP-3025 acetate)

Cat. No.: HY-108009A
Handling Instructions

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp..

For research use only. We do not sell to patients.

Rezafungin acetate Chemical Structure

Rezafungin acetate Chemical Structure

CAS No. : 1631754-41-0

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Description

Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp., Aspergillus spp., and Pneumocystis spp.[1][2].

In Vivo

Rezafungin acetate (Biafungin acetate) (1 mg/kg; i.p. once daily for 6 days) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model[1].

Animal Model: C3H/HeN mice[1]
Dosage: 1 mg/kg
Administration: Intraperitoneal injection; once daily for 6 days
Result: Significantly reduced nuclei and asci burdens.
Clinical Trial
Molecular Weight

1285.44

Formula

C₆₅H₈₈N₈O₁₉

CAS No.

1631754-41-0

SMILES

O=C1N2[[email protected]]([[email protected]@H](O)[[email protected]@H](C)C2)([H])C(N[[email protected]]([[email protected]@H](C[[email protected]@H](C(N[[email protected]]([[email protected]](O)C)([H])C(N3[[email protected]](C[[email protected]@H](O)C3)([H])C(N[[email protected]]([[email protected]](O)[[email protected]](C4=CC=C(O)C=C4)O)([H])C(N[[email protected]@]1([H])[[email protected]](O)C)=O)=O)=O)=O)NC(C5=CC=C(C6=CC=C(C7=CC=C(OCCCCC)C=C7)C=C6)C=C5)=O)O)([H])OCC[N+](C)(C)C)=O.[O-]C(C)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

RezafunginBiafunginCD101SP-3025CD 101CD-101SP3025SP 3025Fungallong-lastingechinocandinantifungalinfectionInhibitorinhibitorinhibit

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Rezafungin acetate
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