Sordarin sodium
Based on 1 Customer Validation
Sordarin sodium is an eEF2 inhibitor and antibiotic. Sordarin sodium's function is dependent on the diphthamide modification on eEF2. Sordarin sodium inhibits protein synthesis by preventing the binding of eEF2 to the ribosome complex. Sordarin sodium has antifungal activity.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 463356-00-5
- Formula: C27H39NaO8
- Molecular Weight:514.58
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
Sordarin sodium (10 µg/mL) can inhibit the growth of Saccharomyces cerevisiae[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 463356-00-5
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Appearance Solid
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Molecular Weight 514.58
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Formula C27H39NaO8
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Color White to off-white
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SMILES
O=C(O[Na])[C@](C(C(C)C)=C[C@H]1C2)([C@]1(CO[C@@H]([C@@H](O)[C@H](O)[C@@H]3OC)O[C@@H]3C)C[C@]4([C@]5(CC[C@H]4C)[H])[H])[C@]25C=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Wael Abdel-Fattah, et al. Insights into diphthamide, key diphtheria toxin effector. Toxins (Basel). 2013 May 3;5(5):958-68. [Content Brief]
[2]. Biprashekhar Chakraborty, et al. Structure-based designing of sordarin derivative as potential fungicide with pan-fungal activity. J Mol Graph Model. 2016 May;66:133-42. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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