1. Anti-infection
  2. Fungal
    Antibiotic
  3. Sordarin sodium

Sordarin sodium 

Cat. No.: HY-126396
Handling Instructions

Sordarin is a potent diphthamide-dependent eEF2 inhibitor with antifungal properties. Sordarin targets eEF2 so as to inhibit protein translation by blocking eEF2-mediated translocation of tRNAs. Sordarin inhibits translation specifically in certain fungi (e.g. C. albicansC. glabrata, and C. neoformans) while unable to do so in some other fungal species (e.g. Candida parapsilosis and Candida lusitaniae).

For research use only. We do not sell to patients.

Sordarin sodium Chemical Structure

Sordarin sodium Chemical Structure

CAS No. : 463356-00-5

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Description

Sordarin is a potent diphthamide-dependent eEF2 inhibitor with antifungal properties. Sordarin targets eEF2 so as to inhibit protein translation by blocking eEF2-mediated translocation of tRNAs. Sordarin inhibits translation specifically in certain fungi (e.g. C. albicansC. glabrata, and C. neoformans) while unable to do so in some other fungal species (e.g. Candida parapsilosis and Candida lusitaniae)[1][2].

IC50 & Target

IC50: eEF2; fungal[1]

Molecular Weight

514.58

Formula

C₂₇H₃₉NaO₈

CAS No.

463356-00-5

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SordarinFungalAntibioticC.?albicansC.?glabrataC.?neoformansCandida parapsilosisCandida lusitaniaeeEF2antifungalInhibitorinhibitorinhibit

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Sordarin sodium
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HY-126396
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