Sordarin
Sordarin (Compound 1) is an antifungal agent targeting Elongation factor 2 (EF2) with a tetracyclic diterpene core including a norbornene system. Sordarin can be isolated from the fungus Sordaria araneosa. Sordarin has potent antifungal activity against Saccharomyces cerevisiae and Candida albicans. Sordarin prevents the translocation of the ribosome along mRNA during elongation of the emerging polypeptide chain, inhibiting protein synthesis in fungi by stabilizing the ribosome/EF2 complex.
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- CAS No.: 11076-17-8
- Formule: C27H40O8
- Masse moléculaire:492.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 11076-17-8
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Masse moléculaire 492.60
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Formule C27H40O8
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SMILES
OC([C@@]1([C@@]([C@@]2([H])[C@]([C@@H](CC2)C)([H])C3)(C4)C=O)[C@]3([C@@]4([H])C=C1C(C)C)CO[C@@H]5O[C@@H]([C@H]([C@H]([C@@H]5O)O)OC)C)=O
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Structure Classification
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Initial Source
Sordaria araneosa
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sordarin Related Classifications
HY-128478 Related Classifications
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