Antifungal agent 96
Antifungal agent 96 (Compound WZ-2) is an antifungal agent with good blood-brain barrier permeability and brain penetration. Antifungal agent 96 inhibits the growth of C. neoformans H99 and C. albicans 0304103 with MIC values of 0.016 and 32 μg/mL, respectively.
For research use only. We do not sell to patients.
- Formula: C11H8N2O3S
- Molecular Weight:248.26
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Antifungal agent 96 (0.063, 2μg/mL; 24 h) significantly inhibits the capsule growth of C. neoformans H99
[1].
Antifungal agent 96 (0.063μg/mL; 24h) inhibits the biofilm formation of C. neoformans H99 with an inhibition rate exceeding 90%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:cryptococcal meningitis (CM) mice[1]
-
Dosage:5 mg/kg
-
Administration:IV; daily for 3 days
-
Result:Significantly reduced the kidney C. albicans 0304103 burden of mice and the brain C. neoformans H99 burden of CM mice.
Chemical Information
-
Molecular Weight 248.26
-
Formula C11H8N2O3S
-
SMILES
O=C(C1=C(/C2=N/OC)C=CS1)C3=C2ON=C3C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 96 Related Classifications
HY-161380 Related Classifications
Powered by Bioz