2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Fungal Cytochrome P450
  4. GlcN-6-P Synthase-IN-1

GlcN-6-P Synthase-IN-1 (Compound 4d) is a Glucosamine-6-phosphate (GlcN-6-P) synthase inhibitor with an IC50 of 3.47 μM. GlcN-6-P Synthase-IN-1 exhibits significant antimicrobial activity. GlcN-6-P Synthase-IN-1 has good penetration in the CNS and is able to inhibit the cytochrome P450, CYP3A4 isoform.

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GlcN-6-P Synthase-IN-1 Chemical Structure

GlcN-6-P Synthase-IN-1 Chemical Structure

CAS No. : 2447602-44-8

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GlcN-6-P Synthase-IN-1 Related Antibodies

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View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP3A4 CYP17A1

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Description

GlcN-6-P Synthase-IN-1 (Compound 4d) is a Glucosamine-6-phosphate (GlcN-6-P) synthase inhibitor with an IC50 of 3.47 μM. GlcN-6-P Synthase-IN-1 exhibits significant antimicrobial activity. GlcN-6-P Synthase-IN-1 has good penetration in the CNS and is able to inhibit the cytochrome P450, CYP3A4 isoform[1].

IC50 & Target

IC50: 3.47 μM (GlcN-6-P synthase)[1]
In Vitro

GlcN-6-P Synthase-IN-1 (Compound 4d) shows antimicrobial activity with MIC values of 1 ± 0.15, 0.5 ± 0.15, 4 ± 0.33 and 4 ± 0.33 µg/mL against S. aureus, B. subtilis, C. albicans and A. oryzae, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GlcN-6-P Synthase-IN-1 Related Antibodies
Molecular Weight

391.49

Formula

C20H21N7S
CAS No.
SMILES

C/C(C1=C(C)N=C(N/N=C/C2=CC=C(C3=CC=CC=C3)C=C2)S1)=N\NC(N)=N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GlcN-6-P Synthase-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GlcN-6-P Synthase-IN-12447602-44-8BacterialFungalCytochrome P450CYPsS. aureusB. subtilisC. albicansA. oryzaeantimicrobialCNS penetrationInhibitorinhibitorinhibit

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