Purpuride
Purpuride is a sesquiterpene ester found in aciduric fungi. Purpuride shows moderate antibacterial activities against Candida albicans, Enterobacter aerogenes and Pseudomonas aeruginosa with MIC values ranging from 1.2 to 3.3 μM.
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- CAS. Nr.: 41411-07-8
- Formel: C22H33NO5
- Molecular Weight:391.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 41411-07-8
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Molecular Weight 391.50
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Formel C22H33NO5
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SMILES
CC(C)[C@@H](C(O[C@H]([C@@]12C)CCC(C)(C)[C@]1([H])CCC3=C2COC3=O)=O)NC(C)=O
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Structure Classification
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Initial Source
Penicillium purpurogenum
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Reinheit & Dokumentation
Verweise
[1]. Wang H, et al. Purpurides B and C, two new sesquiterpene esters from the aciduric fungus Penicillium purpurogenum JS03-21. Chem Biodivers. 2013 Jul;10(7):1185-92. [Content Brief]
[2]. King TJ, et al. Studies in mycological chemistry. XXX and last. Isolation and structure of purpuride, a metabolite of Penicillium purpurogenum Stoll. J Chem Soc Perkin 1. 1973;1:78-80. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)