(-)-Dicentrine
Based on 1 Customer Validation
(-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 28832-07-7
- Formula: C20H21NO4
- Molecular Weight:339.39
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | ED50 |
1.7 μg/mL
Compound: 7
|
Cytotoxicity against human A431 cells after 3 days by SRB assay
Cytotoxicity against human A431 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| HT-1080 | ED50 |
1.7 μg/mL
Compound: 7
|
Cytotoxicity against human HT1080 cells after 3 days by SRB assay
Cytotoxicity against human HT1080 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| KB | ED50 |
1.6 μg/mL
Compound: 7
|
Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
|
[PMID: 8254346] |
| KB-V1 | ED50 |
0.9 μg/mL
Compound: 7
|
Cytotoxicity against vinblastine-resistant human KBV1 cells after 3 days by SRB assay
Cytotoxicity against vinblastine-resistant human KBV1 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| LNCaP | ED50 |
1.9 μg/mL
Compound: 7
|
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
Cytotoxicity against human LNCAP cells after 3 days by SRB assay
|
[PMID: 8254346] |
| P388 | ED50 |
0.6 μg/mL
Compound: 7
|
Cytotoxicity against mouse P388 cells after 3 days by SRB assay
Cytotoxicity against mouse P388 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| SK-MEL-2 | ED50 |
3.8 μg/mL
Compound: 7
|
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| U-373MG ATCC | ED50 |
1.5 μg/mL
Compound: 7
|
Cytotoxicity against human U373 cells after 3 days by SRB assay
Cytotoxicity against human U373 cells after 3 days by SRB assay
|
[PMID: 8254346] |
| ZR-75-1 | ED50 |
2.8 μg/mL
Compound: 7
|
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
Cytotoxicity against human ZR-75-1 cells after 3 days by SRB assay
|
[PMID: 8254346] |
Chemical Information
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CAS No. 28832-07-7
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Appearance Solid
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Molecular Weight 339.39
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Formula C20H21NO4
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Color Light yellow to yellow
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SMILES
CN1CCC(C2=C3C4=CC(OC)=C(OC)C=C4C[C@@]12[H])=CC5=C3OCO5
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Synonyms
L-Dicentrine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)