Fenchyl alcohol
Based on 1 Customer Validation
Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 1632-73-1
- 分子式: C10H18O
- 分子量:154.25
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Fenchyl alcohol has a strong inhibitory effect on rumen microbial activity and inhibits rumen microbial fermentation activity[1].
Fenchyl alcohol (0.005-0.01%; 4-24 h) inhibits the formation of Candida albicans biofilm and hyphae, and inhibits the metabolism of biofilm cells [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:C. albicans cells
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Concentration:0.01%
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Incubation Time:4 h
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Result:Significantly downregulated the expression of ECE1, ECE2, and RBT1.
体内実験
In rats treated with Fenchyl alcohol (2.05, 2.56, 3.2, 4.0, and 5.0 g/kg, orally, single-dose, observed for 14 days), all rat deaths occurred between days 1 and 3. At the 2.05 and 2.56 g/kg doses, half of the animals died; at 3.2 g/kg, three-thirds died; at 4.0 g/kg, two-half died; and at 5.0 g/kg, all five-fifths died[4].
Fenchyl alcohol is administered topically at a dose of 2.0 g/kg body weight, and observed for 14 days. No deaths occurred in either of the two guinea pigs in the experimental group[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1632-73-1
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性状 <43°C Solid,>46°C Liquid
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分子量 154.25
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分子式 C10H18O
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Color Colorless to light yellow
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SMILES
OC1C(C2)(C)CCC2C1(C)C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (324.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 40 mg/mL (259.32 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Oh HK, et al. Effect of Various Essential Oils Isolated from Douglas Fir Needles upon Sheep and Deer Rumen Microbial Activity. Appl Microbiol. 1967 Jul;15(4):777-84. [Content Brief]
[2]. Manoharan RK, et al. Antibiofilm and Antihyphal Activities of Cedar Leaf Essential Oil, Camphor, and Fenchone Derivatives against Candida albicans. Front Microbiol. 2017 Aug 3;8:1476. [Content Brief]
[3]. Api AM, et al. RIFM fragrance ingredient safety assessment, Fenchyl alcohol, CAS registry number 1632-73-1. Food Chem Toxicol. 2015 Oct;84 Suppl:S25-32. [Content Brief]
[4]. Bhatia SP, et al. Fragrance material review on fenchyl alcohol. Food Chem Toxicol. 2008 Nov;46 Suppl 11:S157-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 6.4830 mL | 32.4149 mL | 64.8298 mL | 162.0746 mL |
| 5 mM | 1.2966 mL | 6.4830 mL | 12.9660 mL | 32.4149 mL | |
| 10 mM | 0.6483 mL | 3.2415 mL | 6.4830 mL | 16.2075 mL | |
| 15 mM | 0.4322 mL | 2.1610 mL | 4.3220 mL | 10.8050 mL | |
| 20 mM | 0.3241 mL | 1.6207 mL | 3.2415 mL | 8.1037 mL | |
| 25 mM | 0.2593 mL | 1.2966 mL | 2.5932 mL | 6.4830 mL | |
| 30 mM | 0.2161 mL | 1.0805 mL | 2.1610 mL | 5.4025 mL | |
| 40 mM | 0.1621 mL | 0.8104 mL | 1.6207 mL | 4.0519 mL | |
| 50 mM | 0.1297 mL | 0.6483 mL | 1.2966 mL | 3.2415 mL | |
| 60 mM | 0.1080 mL | 0.5402 mL | 1.0805 mL | 2.7012 mL | |
| 80 mM | 0.0810 mL | 0.4052 mL | 0.8104 mL | 2.0259 mL | |
| 100 mM | 0.0648 mL | 0.3241 mL | 0.6483 mL | 1.6207 mL |
Fenchyl alcohol 関連分類
HY-N7107 関連分類
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