Antifungal agent 52
Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization.
For research use only. We do not sell to patients.
- CAS No.: 2901064-06-8
- Formula: C25H19BrClFN6O
- Molecular Weight:553.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Antifungal agent 52 (compound 6c) (16 μg/mL, 18 h) treated cells enter the G0/G1 phase (metabolic state/cell proliferation) to maintain the daughter cells[1].
Antifungal agent 52 shows significant toxicity at >64 μg/mL and a lack of toxicity against cancer buccal cell line TR146[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2901064-06-8
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Molecular Weight 553.81
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Formula C25H19BrClFN6O
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SMILES
O=C1N(CCCN2N=C(C3=CC=C(Cl)C=C3)N=N2)C4=CC=C(F)C=C4C(C5=CC=CC=C5Br)=NC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 52 Related Classifications
HY-143335 Related Classifications
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