2. Anti-infection
  3. Fungal
  4. Antifungal agent 52

Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization.

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Antifungal agent 52 Chemical Structure

Antifungal agent 52 Chemical Structure

CAS No. : 2901064-06-8

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Antifungal agent 52 Related Antibodies

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Description

Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization[1].

In Vitro

Antifungal agent 52 (compound 6c) (16 μg/mL, 18 h) treated cells enter the G0/G1 phase (metabolic state/cell proliferation) to maintain the daughter cells[1].
Antifungal agent 52 shows significant toxicity at >64 μg/mL and a lack of toxicity against cancer buccal cell line TR146[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antifungal agent 52 Related Antibodies
Molecular Weight

553.81

Formula

C25H19BrClFN6O
CAS No.
SMILES

O=C1N(CCCN2N=C(C3=CC=C(Cl)C=C3)N=N2)C4=CC=C(F)C=C4C(C5=CC=CC=C5Br)=NC1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antifungal agent 52 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 522901064-06-8Antifungal agent52Antifungal agent-52FungalCandida cellscancer buccal cell lineTR146Vero cellsInhibitorinhibitorinhibit

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