Antifungal agent 52
Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2901064-06-8
- 分子式: C25H19BrClFN6O
- 分子量:553.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Antifungal agent 52 (compound 6c) (16 μg/mL, 18 h) treated cells enter the G0/G1 phase (metabolic state/cell proliferation) to maintain the daughter cells[1].
Antifungal agent 52 shows significant toxicity at >64 μg/mL and a lack of toxicity against cancer buccal cell line TR146[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2901064-06-8
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分子量 553.81
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分子式 C25H19BrClFN6O
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SMILES
O=C1N(CCCN2N=C(C3=CC=C(Cl)C=C3)N=N2)C4=CC=C(F)C=C4C(C5=CC=CC=C5Br)=NC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)