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  4. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine  (Synonyms: THEED; THEEN)

Cat. No.: HY-W047709 Purity: 99.89%
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SDS
Handling Instructions Technical Support

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (THEED; THEEN) is a tetrapodal pentadentate chelating ligand that functions as a chelator to form stable complexes with metal ions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine serves as a versatile building block for organic synthesis, a reagent for metal extraction, and an auxiliary for catalytic reactions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine-derived metal complexes exhibit antibacterial, antifungal, and anticancer activities. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine and its metal complexes can be used for research related to breast cancer, leukemia, various bacterial and fungal infections.

For research use only. We do not sell to patients.

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Chemical Structure

CAS No. : 140-07-8

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
250 g In-stock
500 g In-stock
1 kg In-stock

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N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Related Antibodies

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Description

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (THEED; THEEN) is a tetrapodal pentadentate chelating ligand that functions as a chelator to form stable complexes with metal ions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine serves as a versatile building block for organic synthesis, a reagent for metal extraction, and an auxiliary for catalytic reactions. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine-derived metal complexes exhibit antibacterial, antifungal, and anticancer activities. N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine and its metal complexes can be used for research related to breast cancer, leukemia, various bacterial and fungal infections[1][2][3].

In Vitro

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (as its copper(II) complexes) shows inhibitory effects against Staphylococcus aureus, Serratia marcescens, Sphingobium japonicum, Stenotrophomonas maltophilia, Candida albicans, Aspergillus niger, and Saccharomyces cerevisiae with minimum inhibitory concentrations ranging from 25 to 50 μg/mL[1][2][3].
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (as its copper(II) complexes) (48 h) shows in vitro antiproliferative activity against MCF-7, HL-60 and HCT-116 cancer cells[1].
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine (as its copper(II) complexes) (48 h) exhibits potent cytotoxicity against MCF-7 breast cancer cells with an IC50 value of 23 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Related Antibodies
Molecular Weight

236.31

Formula

C10H24N2O4
CAS No.
Appearance

Liquid (Density: 1.193±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

OCCN(CCO)CCN(CCO)CCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (846.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2317 mL 21.1586 mL 42.3173 mL
5 mM 0.8463 mL 4.2317 mL 8.4635 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.89%

SDS (394 KB)

COA (244 KB) HNMR (129 KB) RP-HPLC (241 KB) LCMS (329 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2317 mL 21.1586 mL 42.3173 mL 105.7932 mL
5 mM 0.8463 mL 4.2317 mL 8.4635 mL 21.1586 mL
10 mM 0.4232 mL 2.1159 mL 4.2317 mL 10.5793 mL
15 mM 0.2821 mL 1.4106 mL 2.8212 mL 7.0529 mL
20 mM 0.2116 mL 1.0579 mL 2.1159 mL 5.2897 mL
25 mM 0.1693 mL 0.8463 mL 1.6927 mL 4.2317 mL
30 mM 0.1411 mL 0.7053 mL 1.4106 mL 3.5264 mL
40 mM 0.1058 mL 0.5290 mL 1.0579 mL 2.6448 mL
50 mM 0.0846 mL 0.4232 mL 0.8463 mL 2.1159 mL
60 mM 0.0705 mL 0.3526 mL 0.7053 mL 1.7632 mL
80 mM 0.0529 mL 0.2645 mL 0.5290 mL 1.3224 mL
100 mM 0.0423 mL 0.2116 mL 0.4232 mL 1.0579 mL
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N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine140-07-8THEED THEENBiochemical Assay ReagentsBacterialFungalCandida albicansGram-negative bacteriaAspergillus nigerGram-positive bacteriabreast cancerStaphylococcus aureusSerratia marcescensSaccharomyces cerevisiaefungal speciesleukemiaInhibitorinhibitorinhibit

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