FDH1 Protein, Candida boidinii (C23S, C262A, His, Strep)
FDH1 protein serves as a catalyst in the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity represents the conclusive step in the methanol oxidation pathway within methylotrophic microorganisms. Beyond its involvement in methylotrophic organisms, FDH1 also plays a crucial role in non-methylotrophic organisms, where it contributes to the detoxification of exogenous formate. FDH1 Protein, Candida boidinii (C23S, C262A, His, Strep) is the recombinant Candida boidinii-derived FDH1, expressed by E. coli, with Strep, His labeled tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
FDH1 protein serves as a catalyst in the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity represents the conclusive step in the methanol oxidation pathway within methylotrophic microorganisms. Beyond its involvement in methylotrophic organisms, FDH1 also plays a crucial role in non-methylotrophic organisms, where it contributes to the detoxification of exogenous formate. FDH1 Protein, Candida boidinii (C23S, C262A, His, Strep) is the recombinant Candida boidinii-derived FDH1, expressed by E. coli, with Strep, His labeled tag.
The FDH1 protein is an enzyme that plays a crucial role in methylotrophic microorganisms by catalyzing the NAD(+)-dependent oxidation of formate to carbon dioxide. This enzymatic activity is the final step in the methanol oxidation pathway. Additionally, FDH1 has a significant role in non-methylotrophic organisms where it participates in the detoxification of exogenous formate, contributing to cellular homeostasis and preventing the accumulation of potentially harmful formate levels.
Technical Parameters
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Species Human
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Source E. coli
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Tag Strep;His
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Accession
O13437 (K2-K364, C23S, C262A)
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Gene ID/
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Protein Length
Full Length
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Synonyms
Formate dehydrogenase; EC:1.17.1.9; FDH; NAD-dependent formate dehydrogenase; FDH1; FDH; FDH3
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AA Sequence
KIVLVLYDAGKHAADEEKLYGSTENKLGIANWLKDQGHELITTSDKEGETSELDKHIPDADIIITTPFHPAYITKERLDKAKNLKLVVVAGVGSDHIDLDYINQTGKKISVLEVTGSNVVSVAEHVVMTMLVLVRNFVPAHEQIINHDWEVAAIAKDAYDIEGKTIATIGAGRIGYRVLERLLPFNPKELLYYDYQALPKEAEEKVGARRVENIEELVAQADIVTVNAPLHAGTKGLINKELLSKFKKGAWLVNTARGAIAVAEDVAAALESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAEGTKNILESFFTGKFDYRPQDIILLNGEYVTKAYGKHDKK
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Predicted Molecular Mass
42.8 kDa
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Purity
≥ 80%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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