7-(Carboxymethoxy)-4-methylcoumarin
Based on 1 Customer Validation
7-(Carboxymethoxy)-4-methylcoumarin (Compound VIIIa) is the antibacterial and antifungal agent that exhibits inhibitory activity against S. aureus, B. cereus, S. lutea, C. albicans, C. glabrata, and C. parapsilosis.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 64700-15-8
- Formula: C12H10O5
- Molecular Weight:234.20
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
0.07 nM
Compound: 7-(Carboxymethoxy)-4-methyl coumarin
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Anti-Herpes simplex virus type-1 activity in vero cells using plaque inhibition assay
Anti-Herpes simplex virus type-1 activity in vero cells using plaque inhibition assay
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[PMID: 10464017] |
Chemical Information
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CAS No. 64700-15-8
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Appearance Solid
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Molecular Weight 234.20
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Formula C12H10O5
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Color White to off-white
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SMILES
CC1=CC(OC2=C1C=CC(OCC(O)=O)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (426.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2699 mL | 21.3493 mL | 42.6985 mL | 106.7464 mL |
| 5 mM | 0.8540 mL | 4.2699 mL | 8.5397 mL | 21.3493 mL | |
| 10 mM | 0.4270 mL | 2.1349 mL | 4.2699 mL | 10.6746 mL | |
| 15 mM | 0.2847 mL | 1.4233 mL | 2.8466 mL | 7.1164 mL | |
| 20 mM | 0.2135 mL | 1.0675 mL | 2.1349 mL | 5.3373 mL | |
| 25 mM | 0.1708 mL | 0.8540 mL | 1.7079 mL | 4.2699 mL | |
| 30 mM | 0.1423 mL | 0.7116 mL | 1.4233 mL | 3.5582 mL | |
| 40 mM | 0.1067 mL | 0.5337 mL | 1.0675 mL | 2.6687 mL | |
| 50 mM | 0.0854 mL | 0.4270 mL | 0.8540 mL | 2.1349 mL | |
| 60 mM | 0.0712 mL | 0.3558 mL | 0.7116 mL | 1.7791 mL | |
| 80 mM | 0.0534 mL | 0.2669 mL | 0.5337 mL | 1.3343 mL | |
| 100 mM | 0.0427 mL | 0.2135 mL | 0.4270 mL | 1.0675 mL |
7-(Carboxymethoxy)-4-methylcoumarin Related Classifications
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