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United States

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Cat. No.: HY-P5625

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ROAD-1

ROAD-1 is an oral mucosal α-defensin of Rhesus Macaque. ROAD-1 is active against S. aureus, E. coli, and C. albicans.

For research use only. We do not sell to patients.

Formula: C₁₄₅H₂₄₅N₆₁O₄₄S₆
Molecular Weight:3739.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ROAD-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ROAD-1 is an oral mucosal α-defensin of Rhesus Macaque. ROAD-1 is active against S. aureus, E. coli, and C. albicans^[1].

Chemical Information

Molecular Weight 3739.27
Formula C₁₄₅H₂₄₅N₆₁O₄₄S₆
Sequence

Arg-Arg-Thr-Cys-His-Cys-Arg-Ser-Arg-Cys-Leu-Arg-Arg-Glu-Ser-Asn-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Phe-Ser-Leu-Cys-Cys-Arg (Disulfide bridge:Cys4-Cys31; Cys6-Cys20; Cys10-Cys30)
Sequence Shortening

RRTCHCRSRCLRRESNSGSCNINGRIFSLCCR (Disulfide bridge:Cys4-Cys31; Cys6-Cys20; Cys10-Cys30)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Vasudevan S, et, al. Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque. J Biol Chem. 2008 Dec 19;283(51):35869-77. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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