1. Anti-infection
    Metabolic Enzyme/Protease
  2. Fungal
    Cytochrome P450
  3. Oteseconazole

Oteseconazole (Synonyms: VT-1161)

Cat. No.: HY-17643 Purity: 99.56%
Handling Instructions

Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.

For research use only. We do not sell to patients.

Oteseconazole Chemical Structure

Oteseconazole Chemical Structure

CAS No. : 1340593-59-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 406 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
25 mg USD 990 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51[1][2].

Clinical Trial
Molecular Weight

527.39

Formula

C₂₃H₁₆F₇N₅O₂

CAS No.

1340593-59-0

SMILES

O[[email protected]@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OCC(F)(F)F)C=C4)C=N3)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 270 mg/mL (511.96 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8961 mL 9.4806 mL 18.9613 mL
5 mM 0.3792 mL 1.8961 mL 3.7923 mL
10 mM 0.1896 mL 0.9481 mL 1.8961 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.25 mg/mL (4.27 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.25 mg/mL (4.27 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

OteseconazoleVT-1161VT1161VT 1161FungalCytochrome P450CYPsInhibitorinhibitorinhibit

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Product name:
Oteseconazole
Cat. No.:
HY-17643
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