Antifungal agent 60
Antifungal agent 60 (compound 16) is an inhibitor of ergosterol biosynthesis with broad-spectrum antifungal activity. Antifungal agent 60 inhibits 7 human pathogenic fungal species, 2 fluconazole-resistant C. albicans isolates and 2 multi-drug resistant Candida auris isolates. Antifungal agent 60 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Formula: C22H18F2N4O2
- Molecular Weight:408.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
88.5 μg/mL
Compound: 16
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Cytotoxicity against HUVEC cells assessed as reduction in cell survival incubated for 24 hrs by CCK-8 assay
Cytotoxicity against HUVEC cells assessed as reduction in cell survival incubated for 24 hrs by CCK-8 assay
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[PMID: 37216811] |
Chemical Information
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Molecular Weight 408.40
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Formula C22H18F2N4O2
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SMILES
N#CC1=CC=C(C=C1)C#CCO[C@H](C)[C@@](C2=CC=C(C=C2F)F)(CN3N=CN=C3)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 60 Related Classifications
HY-155545 Related Classifications
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