Antifungal agent 60
Antifungal agent 60 (compound 16) is an inhibitor of ergosterol biosynthesis with broad-spectrum antifungal activity. Antifungal agent 60 inhibits 7 human pathogenic fungal species, 2 fluconazole-resistant C. albicans isolates and 2 multi-drug resistant Candida auris isolates. Antifungal agent 60 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C22H18F2N4O2
- 分子量:408.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
88.5 μg/mL
Compound: 16
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Cytotoxicity against HUVEC cells assessed as reduction in cell survival incubated for 24 hrs by CCK-8 assay
Cytotoxicity against HUVEC cells assessed as reduction in cell survival incubated for 24 hrs by CCK-8 assay
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[PMID: 37216811] |
化学情報
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分子量 408.40
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分子式 C22H18F2N4O2
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SMILES
N#CC1=CC=C(C=C1)C#CCO[C@H](C)[C@@](C2=CC=C(C=C2F)F)(CN3N=CN=C3)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antifungal agent 60 関連分類
HY-155545 関連分類
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