Antibacterial agent 218
Antibacterial agent 218 (compound d28) is an orally active sterol 24-C-Methyltransferase inhibitor with the IC50 of 0.273 μM. Antibacterial agent 218 shows antifungal activity against the C.albicans SC5314 with the IC50 of 0.25 μg/mL.
For research use only. We do not sell to patients.
- Formula: C30H24N4OS
- Molecular Weight:488.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BEAS-2B | EC50 |
>50 μg/mL
Compound: d28
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Cytotoxicity against human BEAS-2B cells incubated for 48 hrs by CCK-8 method
Cytotoxicity against human BEAS-2B cells incubated for 48 hrs by CCK-8 method
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[PMID: 38764175] |
| HUVEC | EC50 |
>50 μg/mL
Compound: d28
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Cytotoxicity against human HUVEC cells incubated for 48 hrs by CCK-8 method
Cytotoxicity against human HUVEC cells incubated for 48 hrs by CCK-8 method
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[PMID: 38764175] |
Chemical Information
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Molecular Weight 488.60
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Formula C30H24N4OS
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SMILES
CN1C(C)=C(C(N1C2=CC=CC=C2)=O)N3/C(SC=C3C4=CC5=C(C=C4)C=CC=C5)=N/C6=CC=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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