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Cat. No.: HY-N14171

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Epicorazine A

Epicorazine A has activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococcus (VRE), MICs of 12.5-25 μg/mL. Epicorazine A also has effect on Candida albicans with a MIC of 25 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 62256-05-7
Formula: C₁₈H₁₆N₂O₆S₂
Molecular Weight:420.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Epicorazine A Chemical Structure

CAS No.: 62256-05-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.3 μM Compound: 4	Cytotoxicity against human A549 cells after 24 hrs by SRB assay Cytotoxicity against human A549 cells after 24 hrs by SRB assay	[PMID: 24370114]
HCT-116	IC₅₀	0.33 μM Compound: 4	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24370114]
HL-60	IC₅₀	0.05 μM Compound: 4	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 24370114]
K562	IC₅₀	1.5 μM Compound: 4	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 24370114]
MGC-803	IC₅₀	2.7 μM Compound: 4	Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay Cytotoxicity against human MGC803 cells after 24 hrs by SRB assay	[PMID: 24370114]

Chemical Information

CAS No. 62256-05-7
Molecular Weight 420.46
Formula C₁₈H₁₆N₂O₆S₂
SMILES

O=C1[C@@]23N(C([C@@]4(SS3)N1[C@@]5([H])[C@](C(C=C[C@@H]5O)=O)([H])C4)=O)[C@@]6([H])[C@](C(C=C[C@@H]6O)=O)([H])C2
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. G Deffieux, et al. New antibiotics from the fungus Epicoccum nigrum. II. Epicorazine A: structure elucidation and absolute configuration. J Antibiot (Tokyo). 1978 Nov;31(11):1102-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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