1. Anti-infection
  2. Fungal
  3. Filastatin

Filastatin 

Cat. No.: HY-124701
Handling Instructions

Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect.

For research use only. We do not sell to patients.

Filastatin Chemical Structure

Filastatin Chemical Structure

CAS No. : 431996-53-1

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Description

Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect[1].

Molecular Weight

359.81

Formula

C₁₈H₁₈ClN₃O₃

CAS No.

431996-53-1

SMILES

O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

FilastatinFungalAntifungalfilamentationadhesionHWP1promoterpolystyreneyeastC. albicansInhibitorinhibitorinhibit

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