10-Undecenoic acid (copper)

Preparations (1.6-3.8 mM; 3-6 h) of 10-Undecenoic acid copper complexed with L-arginine induces apoptosis in tumor cells (A549 and Jurkat)^[2].
10-Undecenoic acid copper (24 h) shows dose-dependent cytotoxicity to human tumor cell lines HeLa, A549, Jurkat, and U937, with IC₅₀s of 0.9862, 0.3751, 0.5782, 0.2893 mM, respectively^[2].
10-Undecenoic acid copper (up to 5 μM) significantly increases the expression and activity of alkaline phosphatase and calcium deposition, and induces the expression of the osteocalcin gene in mouse osteoblastic MC3T3-E1 subclone 4 cells and primary mouse calvarial cells^[3].
10-Undecenoic acid copper reduces the number of viable and active cells and makes the biofilm thinner in C. albicans biofilms, while it increases the cell count, metabolic activity and proteinase activity in C. glabrata biofilms^[4].
10-Undecenoic acid copper (20 μM) shows neuroprotective effect against glutamate, H₂O₂ and Aβ_1-42 induced cell death in SH-SY5Y cells^[5].
10-Undecenoic acid copper (1-40 mM; 6-24 h) reduces the cell death induced by H₂O₂, partially attenuates the cell death induced by Staurosporine (HY-15141) and Ddoxorubicin (HY-15142A) in SH-SY5Y cells^[6].
10-Undecenoic acid copper (12.5-50 μg/mL) causes a reduction of LuxS/AI-2QS system in B. subtilis, and (15.625-250 μg/mL) causes a 10-54% reduction of LasI/LasR QS system in P. aeruginosa^[7].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.