2. Metabolic Enzyme/Protease NF-κB Anti-infection
  3. Endogenous Metabolite NF-κB Fungal
  4. Chitin, from shrimp shells (chitinase substrate)

Chitin, from shrimp shells (chitinase substrate) serves as a substrate for chitinase. Chitin, from shrimp shells (chitinase substrate) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (chitinase substrate) is found in the exoskeleton of crabs. Chitin, from shrimp shells (chitinase substrate) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (chitinase substrate) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (chitinase substrate) can be used in the research of gastric ulcer and candidiasis.

For research use only. We do not sell to patients.

Chitin, from shrimp shells (chitinase substrate)

Chitin, from shrimp shells (chitinase substrate) Chemical Structure

CAS No. : 1398-61-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Chitin, from shrimp shells (chitinase substrate):

Chitin, from shrimp shells (chitinase substrate) Related Antibodies

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Description

Chitin, from shrimp shells (chitinase substrate) serves as a substrate for chitinase. Chitin, from shrimp shells (chitinase substrate) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (chitinase substrate) is found in the exoskeleton of crabs. Chitin, from shrimp shells (chitinase substrate) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (chitinase substrate) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (chitinase substrate) can be used in the research of gastric ulcer and candidiasis[1][2].

IC50 & Target[1]

IL-10

 

In Vitro

Chitin, from shrimp shells (chitinase substrate) shows antifungal activity against 20 clinical isolates of Candida spp.[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chitin, from shrimp shells (chitinase substrate) Related Antibodies
In Vivo

Chitin, from shrimp shells (chitinase substrate) (150-600 mg/kg BW; 13 days) significantly reduces the percentage of gastric ulcer index and inhibits NF-κB p65 expression in the Wistar rat model of ethanol-induced gastric ulcer[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (10-12 weeks old, 190-210 g) with Ethanol-induced gastric ulcer[2]
Dosage: 150, 300, 600 mg/kg
Administration: 13 days
Result: Decreased necrotic cells and fat degeneration, and increased normal cells in gastric mucosa.
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

[Chitin, from shrimp shells (chitinase substrate)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Purity & Documentation
References
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Chitin, from shrimp shells (chitinase substrate) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chitin, from shrimp shells (chitinase substrate)1398-61-4Endogenous MetaboliteNF-κBFungalNuclear factor-κBNuclear factor-kappaBCaco-2 cellsimmunostimulantLactobacillus plantaruminflammatory inducerhuman macrophage chitinasechitinase substratehuman innate immunitychitin-binding domainleishmaniasisinflammatory cytokinesInhibitorinhibitorinhibit

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