Chitin, from shrimp shells (chitinase substrate)
Based on 1 Customer Validation
Chitin, from shrimp shells (chitinase substrate) serves as a substrate for chitinase. Chitin, from shrimp shells (chitinase substrate) is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from shrimp shells (chitinase substrate) is found in the exoskeleton of crabs. Chitin, from shrimp shells (chitinase substrate) inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from shrimp shells (chitinase substrate) exerts antifungal and anti-inflammatory effects. Chitin, from shrimp shells (chitinase substrate) can be used in the research of gastric ulcer and candidiasis.
For research use only. We do not sell to patients.
- CAS No.: 1398-61-4
-
Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
All Endogenous Metabolite Isoforms
More
Biological Activity
|
IL-10 |
Chitin, from shrimp shells (chitinase substrate) shows antifungal activity against 20 clinical isolates of Candida spp.[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Male Wistar rats (10-12 weeks old, 190-210 g) with Ethanol-induced gastric ulcer[2]
-
Dosage:150, 300, 600 mg/kg
-
Administration:13 days
-
Result:Decreased necrotic cells and fat degeneration, and increased normal cells in gastric mucosa.
Chemical Information
-
CAS No. 1398-61-4
-
Appearance Solid
-
Color Light yellow to yellow
-
SMILES
[Chitin, from shrimp shells (chitinase substrate)]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Bernabé P, et al. Chilean crab (Aegla cholchol) as a new source of chitin and chitosan with antifungal properties against Candida spp. Int J Biol Macromol. 2020 Apr 15;149:962-975. [Content Brief]
[2]. Amelia R, et al. Chitin Extracted from the Shell of Blue Swimming Crabs (Portunus pelagicus Linn.) Inhibits NF-kappaB p65 in Ethanol-Induced Gastric Ulcerative Wistar Rats. Mar Drugs. 2023 Sep 12;21(9):488. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Chitin, from shrimp shells (chitinase substrate)
- 1398-61-4
- Endogenous Metabolite
- NF-κB
- Fungal
- Caco-2 cells
- immunostimulant
- Lactobacillus plantarum
- inflammatory inducer
- human macrophage chitinase
- chitinase substrate
- human innate immunity
- chitin-binding domain
- leishmaniasis
- inflammatory cytokines
- Inhibitor
- inhibitor
- inhibit