Chitosan (≥90% deacetylated,viscosity 650-700 mPa.s)
Based on 1 Customer Validation
Chitosan (Deacetylated chitin) (≥90% deacetylated, viscosity 650-700 mPa.s) is a polysaccharide obtained by deacetylating chitin, and exhibits antimicrobial activity against various bacteria and fungi. Chitosan (≥90% deacetylated, viscosity 650-700 mPa.s) can be used as a versatile biomaterial in drug delivery, tissue engineering, and wound healing.
For research use only. We do not sell to patients.
- CAS No.: 9012-76-4
- Molecular Weight:1000000 (Average)
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
Low-molecular-weight chitosan can penetrate bacterial cell walls, bind with DNA and inhibit DNA transcription and mRNA synthesis, while high-molecular-weight Chitosan can bind to the negatively charged components on the bacterial cell wall. It forms an impermeable layer around the cell, changes cell permeability and blocks transport into the cell. Chitosan also can be used in water treatment, wound-healing materials, pharmaceutical excipient or drug carrier, obesity research and as a scaffold for tissue engineering[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9012-76-4
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Appearance Solid
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Molecular Weight 1000000 (Average)
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Color Off-white to light yellow
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SMILES
OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](N)[C@H](O[C@H]3[C@H](O)[C@@H](N)[C@H](O)O[C@@H]3CO)O[C@@H]2CO)[C@H](N)[C@@H](O)[C@@H]1O.[n]
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Synonyms
Deacetylated chitin (≥90% deacetylated,viscosity 650-700 mPa.s); Poly(D-glucosamine) (≥90% deacetylated,viscosity 650-700 mPa.s)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 6.67 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
[2]. Randy Chi Fai Cheung, et al. Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications. Mar Drugs. 2015 Aug 14;13(8):5156-86. [Content Brief]
[3]. Shyr-Yi Lin, et al. Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis. J Cell Biochem. 2007 Apr 15;100(6):1573-80. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Chitosan (≥90% deacetylated,viscosity 650-700 mPa.s)
- 9012-76-4
- Deacetylated chitin (≥90% deacetylated,viscosity 650-700 mPa.s)
- Poly(D-glucosamine) (≥90% deacetylated,viscosity 650-700 mPa.s)
- Environmental Pollutants
- Fungal
- Bacterial
- Biochemical Assay Reagents
- biocompatibility
- biodegradability
- biomaterial
- Inhibitor
- inhibitor
- inhibit