Micafungin-d11 ammonium
Micafungin-d11 ammonium (FK463-d11 ammonium) is the deuterium labeled Micafungin ammonium. Micafungin (FK463) is an antifungal agent and can inhibit β-1,3-glucan synthase. Micafungin inhibits 1,3-β-glucan biosynthesis in fungal cell walls. Micafungin can be used for the research of fungal infection, such as candida infections and aspergillosis.
For research use only. We do not sell to patients.
- Formula: C56H63D11N10O23S
- Molecular Weight:1298.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 235114-32-6
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Molecular Weight 1298.37
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Formula C56H63D11N10O23S
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SMILES
O=S(OC1=CC=C([C@H](O)[C@H]([C@H](NC([C@@](C[C@@H](O)C2)([H])N2C([C@H]([C@H](O)C)N3)=O)=O)C(N[C@@H]([C@H](O)CC(N)=O)C(N4[C@]([C@@H](O)[C@@H](C)C4)([H])C(N[C@H](O)[C@H](O)C[C@H](NC(C5=CC=C(C6=NOC(C7=CC=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C=C7)=C6)C=C5)=O)C3=O)=O)=O)=O)O)C=C1O)(O)=O.N
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Synonyms
FK463-d11 ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Micafungin-d11 ammonium Related Classifications
HY-17579S Related Classifications
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