Betulinic aldehyde oxime
Betulinic aldehyde oxime (Compound 31) is a betulin (HY-N0083) derivative that has antimicrobial properties against E. aerogenes, E. coli, E. faecalis, P. aeruginosa, S. aureus, and C. albicans. Betulinic aldehyde oxime displays cytotoxicity towards hepatocytes, with an IC50 of 25 μM.
For research use only. We do not sell to patients.
- CAS No.: 25613-12-1
- Formula: C30H49NO2
- Molecular Weight:455.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774 | IC50 |
0.3 μM
Compound: 3
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Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced iNOS expression after 24 hrs by Western blot analysis
Antiinflammatory activity against mouse J774 cells assessed as inhibition of LPS-induced iNOS expression after 24 hrs by Western blot analysis
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[PMID: 26915998] |
| J774.A1 | IC50 |
>10 μM
Compound: 17
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Cytotoxicity against mouse J774.A1 cells
Cytotoxicity against mouse J774.A1 cells
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[PMID: 25240731] |
Chemical Information
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CAS No. 25613-12-1
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Molecular Weight 455.72
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Formula C30H49NO2
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SMILES
O/N=C/[C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC4)C)([H])CC3)C)C
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Synonyms
Betulin-28-oxime
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)