Pulvinamide
Pulvinamide is a tetronic acid pigment, a pulvinic acid derivative, an Antibacterial agent and Antifungal agent. Pulvinamide can be isolated from lichens. Pulvinamide weakly inhibits the growth of Bacillus subtilis (ATCC 6633) with an MIC of 50 μg/mL. Pulvinamide weakly inhibits the growth of Candida albicans (ATCC 10231) and Saccharomyces cerevisiae (ATCC 9763), with MIC values of 200 μg/mL and 100 μg/mL, respectively.
For research use only. We do not sell to patients.
- CAS No.: 31673-63-9
- Formula: C18H13NO4
- Molecular Weight:307.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Pulvinamide (50 μg/mL; 48 h) weakly inhibits the growth of Bacillus subtilis (ATCC 6633) with an MIC of 50 μg/mL, and shows no activity against Staphylococcus aureus (ATCC 25923) at concentrations up to 100 μg/mL[1].
Pulvinamide (100-200 μg/mL; 48 h) weakly inhibits the growth of Candida albicans (ATCC 10231) with an MIC of 200 μg/mL and Saccharomyces cerevisiae (ATCC 9763) with an MIC of 100 μg/mL following 48 h incubation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 31673-63-9
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Molecular Weight 307.30
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Formula C18H13NO4
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SMILES
O=C(N)/C(C1=CC=CC=C1)=C(C(O)=C2C3=CC=CC=C3)\OC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pulvinamide Related Classifications
HY-182488 Related Classifications
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