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  3. Chitin synthase inhibitor 5

Chitin synthase inhibitor 5 

Cat. No.: HY-151410
Handling Instructions

Chitin synthase inhibitor 5 (compound 9a) is an inhibitor of chitin synthase with an IC50 value of 0.14 mM. Chitin synthase inhibitor 5 shows broad-spectrum antifungal activity in vitro and shows good inhibition to C. albicans, A. flavus, A. fumigatus and C. neoformans. Chitin synthase inhibitor 5 can be used for the research of fungal.

For research use only. We do not sell to patients.

Chitin synthase inhibitor 5 Chemical Structure

Chitin synthase inhibitor 5 Chemical Structure

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Description

Chitin synthase inhibitor 5 (compound 9a) is an inhibitor of chitin synthase with an IC50 value of 0.14 mM. Chitin synthase inhibitor 5 shows broad-spectrum antifungal activity in vitro and shows good inhibition to C. albicans, A. flavus, A. fumigatus and C. neoformans. Chitin synthase inhibitor 5 can be used for the research of fungal[1].

IC50 & Target

IC50: 0.14 mM (chitin synthase)[1]

In Vitro

Chitin synthase inhibitor 5 (300 μg/mL; 1 h) inhibits chitin synthase with an IC50 value of 0.14 mM[1].
Chitin synthase inhibitor 5 (1-512 μg/mL; 24 h) shows antifungal activities to C. albicans, A. flavus, A. fumigatus and C. neoformans with MIC values of 26.67, 32, 64 and 64 μg/mL, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

500.34

Formula

C23H22BrN3O5

SMILES

COC1=CC2=C(NC(OC23CCN(CC3)C(/C=C/C(NC4=CC=C(C=C4)Br)=O)=O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
Chitin synthase inhibitor 5
Cat. No.:
HY-151410
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