Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol)
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Dimethyloctadecyl[3-(trimethoxysilyl) propyl]ammonium chloride is a quaternary ammonium silane monomer-based disinfectant/antimicrobial agent. Dimethyloctadecylammonium chloride exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as fungicidal activity against Candida albicans in solution; it can form a hydrophobic glass coating that displays bactericidal activity against Gram-positive and Gram-negative bacteria but has limited fungicidal activity against Candida albicans.
For research use only. We do not sell to patients.
- CAS No.: 27668-52-6
- Formula: C26H58ClNO3Si
- Molecular Weight:496.29
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Storage:
Solution, -20°C, 2 years
![Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol) Chemical Structure](https://file.medchemexpress.com/product_pic/hy-w010790.gif "Click to View Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol) Chemical Structure")
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Dimethyloctadecyl[3-(trimethoxysilyl) propyl]ammonium chloride (24 h) acts as a bactericide against Staphylococcus aureus (MIC = 3.9 μg/mL, MBC = 3.9 μg/mL) and Escherichia coli (MIC = 62.5 μg/mL, MBC = 62.5 μg/mL), and also functions as a fungicide against Candida albicans (MIC = 15.6 μg/mL, MFC = 62.5 μg/mL)[1].
Dimethyloctadecyl[3-(trimethoxysilyl) propyl]ammonium chloride (62.5 μg/mL; 24 h) exhibits high toxicity toward human skin fibroblasts, HaCaT keratinocytes and HEK293 cells[1].
The coating formed on the surfaces of glass coverslips and Lava™ Ultimate dental restorative material by dimethyloctadecyl[3-(trimethoxysilyl) propyl]ammonium chloride (10 mg/mL; 24 h) exhibits strong antibacterial activity against Staphylococcus aureus and Escherichia coli, but shows negligible activity against Candida albicans[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 27668-52-6
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Appearance Liquid
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Molecular Weight 496.29
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Formula C26H58ClNO3Si
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SMILES
[Cl-].O(C)[Si](OC)(OC)CCC[N+](C)(C)CCCCCCCCCCCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol) Related Classifications
HY-W010790 Related Classifications
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Keywords
- Dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (42% w/w in methanol)
- 27668-52-6
- Bacterial
- Fungal
- human skin cells
- human kidney cells
- Staphylococcus aureus
- Gram-negative bacteria
- Gram-positive bacteria
- human dermal fibroblasts
- Escherichia coli
- Candida albicans
- HaCaT keratinocytes
- HEK293 cells
- Inhibitor
- inhibitor
- inhibit