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  3. Temporin A

Temporin A 

Cat. No.: HY-P1629
Handling Instructions

Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Temporin A Chemical Structure

Temporin A Chemical Structure

CAS No. : 188713-69-1

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Description

Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria. Temporin A is effective against a broad spectrum of Gram-positive bacteria. Temporin A interacts directly with the cell membrane of the microorganism and it is non-toxic to erythrocytes at concentrations that are antimicrobial. Temporin A also has antifungal activities (against yeast-like Candida albicans)[1][1][3].

In Vitro

Temporin A (TA) is a small, basic, highly hydrophobic, antimicrobial peptide amide (FLPLIGRVLSGIL-NH2) found in the skin of the European red frog, Rana temporaria. It has variable antibiotic activities against a broad spectrum of microorganisms, including clinically important Methicillin-sensitive and -resistant Staphylococcus aureus as well as Vancomycin-resistant Enterococcus faecium strains[2].

Molecular Weight

1396.76

Formula

C₆₈H₁₁₇N₁₇O₁₄

CAS No.

188713-69-1

Sequence Shortening

FLPLIGRVLSGIL-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Temporin ABacterialFungalAntibioticantibioticmicroorganismsresistantantimicrobialcellmembraneerythrocytesInhibitorinhibitorinhibit

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