2. Others Anti-infection
  3. Fungal Environmental Pollutants Bacterial
  4. 1,2-Hexanediol

1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation.

For research use only. We do not sell to patients.

1,2-Hexanediol

1,2-Hexanediol Chemical Structure

CAS No. : 6920-22-5

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Other Forms of 1,2-Hexanediol:

1,2-Hexanediol Related Antibodies

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Description

1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation[1][2].

In Vitro

1,2-hexanediol (195-100000 ppm; 24-72 h) inhibits the growth of Escherichia coli NCTC 12923, Staphylococcus aureus NCTC 10788, Candida albicans NCPF 3179, and Aspergillus brasiliensis NCPF 2275, with MIC values of 12500, 25000, 12500, and 6250 ppm, respectively[1].
1,2-hexanediol (0-25000 ppm; 24-48 h) exerts synergistic inhibitory effects with Nicotinamide (HY-B0150) against Candida albicans NCPF 3179 and Aspergillus brasiliensis NCPF 2275, with FICI values of 0.375 and 0.3125, respectively; it exerts synergistic inhibitory effects with sodium cocoyl methyl taurate and sodium cocoyl alaninate against Escherichia coli NCTC 12923, with an FICI value of 0.375 for each combination; it also exerts a synergistic inhibitory effect with sodium C14-16 olefin sulfonate against Aspergillus brasiliensis NCPF 2275, with an FICI value of 0.375[1].
1,2-Hexanediol disrupts the cytoplasmic membrane potential of B. cereus ATCC 21772[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Hexanediol Related Antibodies
Molecular Weight

118.18

Formula

C6H14O2
CAS No.
Appearance

Liquid (Density: 0.951 g/cm3)

Color

Colorless to light yellow

SMILES

OCC(O)CCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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1,2-Hexanediol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,2-Hexanediol6920-22-5Hexane-1,2-diolFungalEnvironmental PollutantsBacterialEnvironmental Contaminantsbacterial cytoplasmic membrane potentialniacinamideStaphylococcus aureus NCTC 10788Aspergillus brasiliensis NCPF 2275fungiEscherichia coli NCTC 12923Gram-positive bacteriaGram-negative bacteriaCandida albicans NCPF 3179Bacillus cereusntimicrobial agentInhibitorinhibitorinhibit

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