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Results for "

adc-linkers

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (2) ADC Linker (842) ADC Payload (2) Amino Acid Derivatives (2) Apoptosis (2) Bacterial (6) Biochemical Assay Reagents (5) Btk (1) CDK (1) DNA/RNA Synthesis (1) Drug Derivative (3) Drug Intermediate (6) Drug-Linker Conjugates for ADC (136) EGFR (1) Environmental Pollutants (1) Epigenetic Reader Domain (1) Estrogen Receptor/ERR (3) Eukaryotic Initiation Factor (eIF) (1) Isotope-Labeled Compounds (4) Kinesin (2) Microtubule/Tubulin (28) NAMPT (1) PROTAC Linkers (212) PROTAC-Linker Conjugates for PAC (4) PROTACs (1) Radionuclide-Drug Conjugates (RDCs) (1) Reference Standards (10) Sodium Phosphate Cotransporter (1) TNF Receptor (1) Topoisomerase (25)
By Research Areas:	Cancer (958) Infection (6) Inflammation/Immunology (30) Neurological Disease (3)
Click Chemistry:	ADC Synthesis (255) Labeling and Fluorescence Imaging (1) TCO (24) DBCO (65) PROTAC Synthesis (54) BCN (32) Azide (82) Tetrazine (51) Alkynes (49)

999

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

296

Click Chemistry

GMP Molecules

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-133540

Maleimide-DOTA 2 Publications Verification Maleimido-mono-amide-DOTA	ADC Linker	Inflammation/Immunology Cancer
Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W002213

N-Hydroxysulfosuccinimide sodium 2 Publications Verification	ADC Linker	Cancer
N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-12362

Val-cit-PAB-OH 1 Publications Verification	ADC Linker	Cancer
Val-cit-PAB-OH is a degradable ADC linker.

HY-42146

BMPS	ADC Linker	Cancer
BMPS is a nonclaevable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs).

HY-44246

MC-Gly-Gly-Phe-Gly 2 Publications Verification Mc-GGFG-OH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-126364

Mc-Val-Ala-PAB	ADC Linker	Cancer
Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-140014

Val-Cit	ADC Linker	Cancer
Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-44221

*MAC glucuronide linker-1*	ADC Linker	Cancer
MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs) .

HY-W023121

Fmoc-Gly-Gly-OH	ADC Linker	Cancer
Fmoc-Gly-Gly-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-125933

Val-Ala-PAB	ADC Linker	Cancer
Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis .

HY-101151

sulfo-SPDB	ADC Linker	Cancer
sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-101153

MC-Val-Ala-OH 1 Publications Verification	ADC Linker	Cancer
MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-12448

SPDB	ADC Linker	Cancer
SPDB is a glutathione cleavable *ADC linker* used for the antibody-drug conjugate (ADCs) .

HY-41919

Mal-L-PA-NH-Boc mDPR(boc); (S)-MALEOYL-DPR(BOC)-OH·DCHA	ADC Linker	Cancer
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-W011541

SIA Crosslinker Iodoacetic acid N-hydroxysuccinimide ester; N-Succinimidyl Iodoacetate	ADC Linker	Cancer
SIA Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-141141

Boc-Val-Cit-PAB	ADC Linker	Cancer
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-135418

Fmoc-Asp-NH2	ADC Linker	Cancer
Fmoc-Asp-NH2 is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs).

HY-140098

Boc-Cystamine	ADC Linker	Cancer
Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140129

NHS-SS-biotin	ADC Linker	Cancer
NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-48692

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)	ADC Linker	Cancer
Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.

HY-140140

PC Mal-NHS carbonate ester	ADC Linker	Cancer
PC Mal-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-170534

Ac-EEVC-OH	ADC Linker	Cancer
Ac-EEVC-OH is a *ADC Linker* that can be used for the synthesis of ADC molecules .

HY-150043A

MDTF	ADC Linker	Cancer
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126495A

Sulfo-LC-SPDP sodium	ADC Linker	Cancer
Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-159794

Azido-methyltetrazine di-arm linker	ADC Linker	Cancer
Azido-methyltetrazine di-arm linker is a multivalent *ADC linker* for the synthesis of antibody-drug conjugates (ADCs) .

HY-129362

Phe-Lys(Fmoc)-PAB	ADC Linker	Cancer
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable *ADC linker* used for the antibody-drug conjugates (ADCs) .

HY-W129833

H-Asp-Gly-OH	ADC Linker	Cancer
H-Asp-Gly-OH is a cleavable ADC linker.

HY-W614632

γ-Glu-Val-Gly	ADC Linker	Cancer
γ-Glu-Val-Gly is a cleavable ADC linker.

HY-49223

diMal-O-CH2COOH	ADC Linker	Cancer
diMal-O-CH2COOH is a cleavable ADC linker.

HY-129368

SPDMV 1 Publications Verification	ADC Linker	Cancer
SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

HY-126405

SMPT	ADC Linker	Cancer
SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140096

Aminoethyl-SS-propionic acid	ADC Linker	Cancer
Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P11295

Fmoc-GGFG-PAB-PNP	ADC Linker	Cancer
Fmoc-GGFG-PAB-PNP is an *ADC linker* used in the synthesis of antibody-drug conjugates (ADC) .

HY-P5299

Fmoc-Gly-Gly-OSu	Biochemical Assay Reagents	Others
Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker .

HY-W744459

DeBoc-Cabazitaxel	ADC Payload	Cancer
DeBoc-Cabazitaxel is an ADC linker.

HY-144628

Fmoc-Asn-Pro-Val-PABC-PNP	ADC Linker	Cancer
Fmoc-Asn-Pro-Val-PABC-PNP (compound 6) is a potent ADC Linker .

HY-160157

IM-2	Drug-Linker Conjugates for ADC	Cancer
IM-2 is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-129360

Ala-Ala-Asn-PAB	ADC Linker	Cancer
Ala-Ala-Asn-PAB is a peptide cleavable *ADC linker* for antibody-drug conjugates (ADCs) .

HY-150043

MDTF free acid	ADC Linker	Cancer
MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-129349

Phe-Lys(Trt)-PAB	ADC Linker	Cancer
Phe-Lys(Trt)-PAB is a cathepsin cleavable *ADC linker* used for the antibody-drug conjugates (ADCs) .

HY-111121

cBu-Cit-OH Mal-cyclobutane-1,1-dicarboxamide-Cit-PAB	ADC Linker	Cancer
cBu-Cit-OH (Mal-cyclobutane-1) is an *ADC Linker* that can be used to synthesize ADCs .

HY-129361

Fmoc-Ala-Ala-Asn-PABC-PNP	ADC Linker	Cancer
Fmoc-Ala-Ala-Asn-PABC-PNP is a peptide cleavable ADC linker .

HY-129371

SPDV	ADC Linker	Cancer
SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

HY-W071006

PPC-NHS ester 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate	ADC Linker	Cancer
PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-133542

Dimethylamine-SPDB	ADC Linker	Cancer
Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-129370

SPDB-sulfo	ADC Linker	Cancer
SPDB-sulfo is a glutathione cleavable *ADC linker* used for the antibody-drug conjugate (ADCs) .

HY-126531

DMAC-PDB	ADC Linker	Cancer
DMAC-PDB is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-140987

5-Maleimidovaleric acid	ADC Linker	Cancer
5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126496

PEG4-SPDP	ADC Linker	Cancer
PEG4-SPDP is a cleavable *ADC linker* used for the antibody-drug conjugates (ADCs).

HY-141158

N-(Iodoacetamido)-Doxorubicin	ADC Linker	Cancer
N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Nombre del producto	Type

HY-126851

Fluorescein-DBCO	Fluorescent Dyes
Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fluorescein-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-123687

DBCO-Sulfo-NHS ester sodium	Fluorescent Dyes
DBCO-Sulfo-NHS ester sodium is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-78921AG

Fmoc-3VVD-OH	Fluorescent Dyes
Fmoc-3VVD-OH (GMP) is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-12362G

Val-cit-PAB-OH	Fluorescent Dyes
Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Val-cit-PAB-OH is a degradable ADC linker.

HY-100374G

Val-Cit-PAB-MMAE	Fluorescent Dyes
Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

HY-20336G

Mc-Val-Cit-PABC-PNP	Fluorescent Dyes
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-131833G

Fmoc-Gly-Gly-Phe-OH	Fluorescent Dyes
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78736G

Val-Cit-PAB-OSBT	Fluorescent Dyes
Val-Cit-PAB-OSBT GMP is a GMP grade Val-Cit-PAB-OSBT (HY-78736). Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together .

HY-133540G

Maleimide-DOTA Maleimido-mono-amide-DOTA	Fluorescent Dyes
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-42972G

DBCO-acid	Fluorescent Dyes
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Fluorescent Dyes
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Fluorescent Dyes
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

Cat. No.	Nombre del producto	Type

HY-78921AG

Fmoc-3VVD-OH	Biochemical Assay Reagents
Fmoc-3VVD-OH (GMP) is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-12362G

Val-cit-PAB-OH	Biochemical Assay Reagents
Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Val-cit-PAB-OH is a degradable ADC linker.

HY-100374G

Val-Cit-PAB-MMAE	Biochemical Assay Reagents
Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

HY-20336G

Mc-Val-Cit-PABC-PNP	Biochemical Assay Reagents
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-131833G

Fmoc-Gly-Gly-Phe-OH	Biochemical Assay Reagents
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78736G

Val-Cit-PAB-OSBT	Biochemical Assay Reagents
Val-Cit-PAB-OSBT GMP is a GMP grade Val-Cit-PAB-OSBT (HY-78736). Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together .

HY-133540G

Maleimide-DOTA Maleimido-mono-amide-DOTA	Biochemical Assay Reagents
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-42972G

DBCO-acid	Biochemical Assay Reagents
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Biochemical Assay Reagents
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-135928

Biotin-C2-S-S-pyridine	Biochemical Assay Reagents
Biotin-C2-S-S-pyridine is a cleavable *ADC linker. Biotin-C2-S-S-pyridine can be used in the synthesis of antibody-drug conjugates (ADCs*) .

HY-163789

Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide	Biochemical Assay Reagents
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Biochemical Assay Reagents
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

Cat. No.	Nombre del producto	Target	Research Area

HY-P3669

Gly-Gly-Phe-Gly	ADC Linker Drug Intermediate	Cancer
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .

HY-136432

Mc-Gly-Gly-Phe-Gly-PAB-OH Mc-GGFG-PAB-OH	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-170534

Ac-EEVC-OH	ADC Linker	Cancer
Ac-EEVC-OH is a *ADC Linker* that can be used for the synthesis of ADC molecules .

HY-W008064

Fmoc-Cit-OH Fmoc-L-Citrulline	Amino Acid Derivatives	Cancer
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif .

HY-P11295

Fmoc-GGFG-PAB-PNP	ADC Linker	Cancer
Fmoc-GGFG-PAB-PNP is an *ADC linker* used in the synthesis of antibody-drug conjugates (ADC) .

HY-P5299

Fmoc-Gly-Gly-OSu	Biochemical Assay Reagents	Others
Fmoc-Gly-Gly-OSu (Compound 98-6) is a dipeptide that can be used to synthesize ADC linker .

HY-136432A

Mc-Gly-Gly-Phe-Gly-PAB-OH TFA Mc-GGFG-PAB-OH TFA	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-P2376

Arg-Phe-Asp-Ser	ADC Linker	Cancer
Arg-Phe-Asp-Ser is a cleavable ADC linker.

HY-W1050525

Fmoc-Val-Ala-Gly	ADC Linker	Cancer
Fmoc-Val-Ala-Gly (compound 58a) is a cleavable ADC linker, can be conjugated to the antibody Trastuzumab (HY-P9907) to form an antibody-drug conjugate (ADC) .

HY-W729138

Fmoc-D-homoArg(Et)2-OH hydrochloride	ADC Linker	Others
Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs) .

Cat. No.	Nombre del producto	Target	Research Area	Image

HY-P9980

Belantamab 2 Publications Verification GSK2857914	ADC Antibody TNF Receptor	Cancer
Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .

HY-P99970

Lifastuzumab	ADC Antibody Sodium Phosphate Cotransporter	Cancer
Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody. Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) (HY-15162) through ADC Linker to form an antibody-drug conjugate (ADC) Lifastuzumab vedotin (HY-P99705) with anticancer activity. Lifastuzumab vedotin can be studied in research for non-small cell lung cancer and ovarian cancer. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-W034595

Eicosanedioic acid	Microorganisms Source Classification	ADC Linker PROTAC Linkers
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

HY-W034918

Docosanedioic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Plants Disease Research Fields Source Classification Cancer	ADC Linker PROTAC Linkers
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-W034918R

Docosanedioic acid (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Plants Source Classification	ADC Linker Reference Standards PROTAC Linkers
Docosanedioic acid (Standard) is the analytical standard of Docosanedioic acid (HY-W034918). This product is intended for research and analytical applications. Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Cat. No.	Nombre del producto	Chemical Structure

HY-161022S1

FL118-C3-O-C-amide-C-NH2-d5 formate
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-79369S

Succinic anhydride-d4
Succinic anhydride-d₄ is the deuterium labeled Succinic anhydride. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide .

HY-I1129

Fmoc-3VVD-OH-d8
Fmoc-3VVD-OH-d₈ is a deuterium labeled Fmoc-3VVD-OH (HY-78921). Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-145989S

Aminobenzenesulfonic auristatin E-d8
Aminobenzenesulfonic auristatin E-d₈ is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic .

HY-79369S1

Succinic anhydride-13C2
Succinic anhydride- ¹³C₂ is the ¹³C labeled Succinic anhydride . Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide .

HY-114816S

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d₅ is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-78921AG

Fmoc-3VVD-OH	ADC Linker	Cancer
Fmoc-3VVD-OH (GMP) is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-12362G

Val-cit-PAB-OH	ADC Linker	Cancer
Val-cit-PAB-OH GMP is a GMP grade Val-cit-PAB-OH (HY-12362). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Val-cit-PAB-OH is a degradable ADC linker.

HY-131833G

Fmoc-Gly-Gly-Phe-OH	ADC Linker	Cancer
Fmoc-Gly-Gly-Phe-OH GMP is a GMP grade Fmoc-Gly-Gly-Phe-OH (HY-131833). Fmoc-Gly-Gly-Phe-OH is a cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78736G

Val-Cit-PAB-OSBT	ADC Linker	Cancer
Val-Cit-PAB-OSBT GMP is a GMP grade Val-Cit-PAB-OSBT (HY-78736). Val-Cit-PAB-OSBT is a degradable ADC linker, which is composed of the polypeptide Val-Cit-PAB and OSBT groups coupled together .

HY-133540G

Maleimide-DOTA Maleimido-mono-amide-DOTA	ADC Linker	Inflammation/Immunology Cancer
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable *ADC linker* used in the synthesis of antibody-drug conjugates (ADCs) .

HY-100374G

Val-Cit-PAB-MMAE	Drug-Linker Conjugates for ADC	Cancer
Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

HY-20336G

Mc-Val-Cit-PABC-PNP	ADC Linker	Cancer
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-42972G

DBCO-acid	Biochemical Assay Reagents	Cancer
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

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